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Literature summary for 2.7.1.230 extracted from

  • Hashimoto, M.; Taguchi, T.; Nishida, S.; Ueno, K.; Koizumi, K.; Aburada, M.; Ichinose, K.
    Isolation of 8-phosphate ester derivatives of amicoumacins structure-activity relationship of hydroxy amino acid moiety (2007), J. Antibiot., 60, 752-756 .
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
amicoumacin A + phosphate Bacillus pumilus
-
 amicoumacin A 2-phosphate + H2O
-
 ?
amicoumacin A + phosphate Bacillus pumilus MU313B
-
 amicoumacin A 2-phosphate + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Bacillus pumilus
-
-
-
Bacillus pumilus MU313B
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
amicoumacin A + phosphate
-
 Bacillus pumilus amicoumacin A 2-phosphate + H2O
-
 ?
amicoumacin A + phosphate
-
 Bacillus pumilus MU313B amicoumacin A 2-phosphate + H2O
-
 ?

General Information

General Information Comment Organism
physiological function the antibacterial activity of amicoumacin A is a dramatically decreased by phosphorylation at the C-8 hydroxyl group Bacillus pumilus