Any feedback?
Literature summary for 2.7.1.23 extracted from
- NAD kinases Metabolic targets controlling redox co-enzymes and reducing power partitioning in plant stress and development (2018), Front. Plant Sci., 9, 379 .
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.022 | - |
NAD+ | pH and temperature not specified in the publication | Homo sapiens |  |
| 0.042 | - |
NADH | pH and temperature not specified in the publication | Arabidopsis thaliana | |
| 0.062 | - |
ATP | pH and temperature not specified in the publication | Arabidopsis thaliana | |
| 0.212 | - |
NAD+ | pH and temperature not specified in the publication | Strongylocentrotus purpuratus | |
| 0.263 | - |
ATP | pH and temperature not specified in the publication | Strongylocentrotus purpuratus | |
| 0.397 | - |
ATP | pH and temperature not specified in the publication | Strongylocentrotus purpuratus | |
| 0.4 | - |
ATP | pH and temperature not specified in the publication | Pyrococcus horikoshii | |
| 0.43 | - |
ATP | pH and temperature not specified in the publication | Sphingomonas sp. | |
| 0.43 | - |
NAD+ | pH and temperature not specified in the publication | Arabidopsis thaliana | |
| 0.52 | - |
NAD+ | pH and temperature not specified in the publication | Arabidopsis thaliana | |
| 0.54 | - |
NAD+ | pH and temperature not specified in the publication | Homo sapiens | |
| 0.54 | - |
NAD+ | pH and temperature not specified in the publication | Strongylocentrotus purpuratus | |
| 0.73 | - |
ATP | pH and temperature not specified in the publication | Arabidopsis thaliana | |
| 0.74 | - |
ATP | pH and temperature not specified in the publication | Arabidopsis thaliana | |
| 1 | - |
NAD+ | pH and temperature not specified in the publication | Bacillus subtilis | |
| 1.7 | - |
ATP | pH and temperature not specified in the publication | Homo sapiens | |
| 1.92 | - |
ATP | pH and temperature not specified in the publication | Sphingomonas sp. | |
| 2 | - |
ATP | pH and temperature not specified in the publication | Escherichia coli | |
| 2.39 | - |
NAD+ | pH and temperature not specified in the publication | Arabidopsis thaliana | |
| 2.5 | - |
NAD+ | pH and temperature not specified in the publication | Escherichia coli | |
| 3.3 | - |
ATP | pH and temperature not specified in the publication | Homo sapiens | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| chloroplast | - |
Arabidopsis thaliana | 9507 | - |
| cytosol | - |
Homo sapiens | 5829 | - |
| cytosol | - |
Arabidopsis thaliana | 5829 | - |
| cytosol | - |
Glycine max | 5829 | - |
| cytosol | - |
Strongylocentrotus purpuratus | 5829 | - |
| mitochondrion | - |
Homo sapiens | 5739 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 30000 | - |
subunit | Escherichia coli |
| 35000 | - |
subunit | Arabidopsis thaliana |
| 37000 | - |
subunit | Pyrococcus horikoshii |
| 58200 | - |
subunit | Arabidopsis thaliana |
| 60000 | - |
subunit | Strongylocentrotus purpuratus |
| 109200 | - |
subunit | Arabidopsis thaliana |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + NAD+ | Homo sapiens | - |
ADP + NADP+ | - |
? | |
| ATP + NAD+ | Arabidopsis thaliana | - |
ADP + NADP+ | - |
? | |
| ATP + NAD+ | Pyrococcus horikoshii | - |
ADP + NADP+ | - |
? | |
| ATP + NAD+ | Escherichia coli | - |
ADP + NADP+ | - |
? | |
| ATP + NAD+ | Archaeoglobus fulgidus | - |
ADP + NADP+ | - |
? | |
| ATP + NAD+ | Strongylocentrotus purpuratus | - |
ADP + NADP+ | - |
? | |
| ATP + NAD+ | Sphingomonas sp. | - |
ADP + NADP+ | - |
? | |
| ATP + NAD+ | Bacillus subtilis | - |
ADP + NADP+ | - |
? | |
| ATP + NAD+ | Escherichia coli K12 | - |
ADP + NADP+ | - |
? | |
| ATP + NAD+ | Pyrococcus horikoshii ATCC 700860 | - |
ADP + NADP+ | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Arabidopsis thaliana | Q500Y9 | - |
- |
| Arabidopsis thaliana | Q56YN3 | - |
- |
| Arabidopsis thaliana | Q9C5W3 | - |
- |
| Archaeoglobus fulgidus | P0A7B3 | - |
- |
| Bacillus subtilis | M4KX93 | XF-1 | - |
| Escherichia coli | P0A7B3 | - |
- |
| Escherichia coli K12 | P0A7B3 | - |
- |
| Glycine max | I1KAE3 | - |
- |
| Glycine max | I1LPA7 | - |
- |
| Glycine max | I1LVA5 | - |
- |
| Glycine max | K7LNT1 | - |
- |
| Glycine max | K7LY64 | - |
- |
| Homo sapiens | O95544 | - |
- |
| Homo sapiens | Q4G0N4 | - |
- |
| Pyrococcus horikoshii | O58801 | - |
- |
| Pyrococcus horikoshii ATCC 700860 | O58801 | - |
- |
| Solanum lycopersicum | A0A3Q7E928 | - |
- |
| Solanum lycopersicum | A0A3Q7JHB9 | - |
- |
| Sphingomonas sp. | O58801 | - |
- |
| Strongylocentrotus purpuratus | C3RSF7 | - |
- |
| Strongylocentrotus purpuratus | P21373 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| flower | low expression | Arabidopsis thaliana | - |
| flower | low expression | Glycine max | - |
| flower | moderate expression | Arabidopsis thaliana | - |
| flower | moderate expression | Solanum lycopersicum | - |
| flower | moderate expression | Glycine max | - |
| inflorescence | low expression | Arabidopsis thaliana | - |
| inflorescence | low expression | Glycine max | - |
| inflorescence | moderate expression | Arabidopsis thaliana | - |
| inflorescence | moderate expression | Glycine max | - |
| leaf | high expression | Arabidopsis thaliana | - |
| leaf | low expression | Arabidopsis thaliana | - |
| leaf | low expression | Solanum lycopersicum | - |
| leaf | low expression | Glycine max | - |
| leaf | moderate expression | Glycine max | - |
| root | high expression | Glycine max | - |
| root | low expression | Glycine max | - |
| root | moderate expression | Arabidopsis thaliana | - |
| root | moderate expression | Solanum lycopersicum | - |
| root | moderate expression | Glycine max | - |
| seed | low expression | Arabidopsis thaliana | - |
| seed | low expression | Solanum lycopersicum | - |
| seed | low expression | Glycine max | - |
| seed | moderate expression | Arabidopsis thaliana | - |
| seed | moderate expression | Glycine max | - |
| seedling | high expression | Glycine max | - |
| seedling | low expression | Arabidopsis thaliana | - |
| seedling | low expression | Solanum lycopersicum | - |
| seedling | low expression | Glycine max | - |
| seedling | moderate expression | Arabidopsis thaliana | - |
| seedling | moderate expression | Glycine max | - |
| stem | high expression | Arabidopsis thaliana | - |
| stem | low expression | Arabidopsis thaliana | - |
| stem | low expression | Solanum lycopersicum | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + NAD+ | - |
Homo sapiens | ADP + NADP+ | - |
? | |
| ATP + NAD+ | - |
Arabidopsis thaliana | ADP + NADP+ | - |
? | |
| ATP + NAD+ | - |
Pyrococcus horikoshii | ADP + NADP+ | - |
? | |
| ATP + NAD+ | - |
Escherichia coli | ADP + NADP+ | - |
? | |
| ATP + NAD+ | - |
Archaeoglobus fulgidus | ADP + NADP+ | - |
? | |
| ATP + NAD+ | - |
Strongylocentrotus purpuratus | ADP + NADP+ | - |
? | |
| ATP + NAD+ | - |
Sphingomonas sp. | ADP + NADP+ | - |
? | |
| ATP + NAD+ | - |
Bacillus subtilis | ADP + NADP+ | - |
? | |
| ATP + NAD+ | - |
Escherichia coli K12 | ADP + NADP+ | - |
? | |
| ATP + NAD+ | - |
Pyrococcus horikoshii ATCC 700860 | ADP + NADP+ | - |
? | |
| ATP + NADH | - |
Arabidopsis thaliana | ADP + NADPH | - |
? | |
| CTP + NAD+ | - |
Arabidopsis thaliana | CDP + NADP+ | - |
? | |
| GTP + NAD+ | - |
Arabidopsis thaliana | GDP + NADP+ | - |
? | |
| UTP + NAD+ | - |
Arabidopsis thaliana | UDP + NADP+ | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | 1 * 60000 | Strongylocentrotus purpuratus |
| ? | x * 35000 | Arabidopsis thaliana |
| ? | x * 109200 | Arabidopsis thaliana |
| ? | x * 58200 | Arabidopsis thaliana |
| dimer | 2 * 30000 | Bacillus subtilis |
| dimer | or tetramer | Archaeoglobus fulgidus |
| hexamer | 6 * 30000 | Escherichia coli |
| homodimer | 2 * 45000 | Homo sapiens |
| homotetramer | 4 * 49000 | Homo sapiens |
| tetramer | 2 * 32000 | Sphingomonas sp. |
| tetramer | 4 * 37000 | Pyrococcus horikoshii |
| tetramer | or dimer | Archaeoglobus fulgidus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Afnk | - |
Archaeoglobus fulgidus |
| AtNADK1 | - |
Arabidopsis thaliana |
| AtNADK2 | - |
Arabidopsis thaliana |
| AtNADK3 | - |
Arabidopsis thaliana |
| BsNADK | - |
Bacillus subtilis |
| C5orf33 | - |
Homo sapiens |
| GmNADK1 | - |
Glycine max |
| GmNADK2 | - |
Glycine max |
| GmNADK3 | - |
Glycine max |
| GmNADK4 | - |
Glycine max |
| GmNADK5 | - |
Glycine max |
| NADK | - |
Homo sapiens |
| NADK | - |
Sphingomonas sp. |
| NADK2 | - |
Homo sapiens |
| PH1074 | - |
Pyrococcus horikoshii |
| SlNADK1 | - |
Solanum lycopersicum |
| SlNADK2 | - |
Solanum lycopersicum |
| SpNADK1 | - |
Strongylocentrotus purpuratus |
| SpNADK2 | - |
Strongylocentrotus purpuratus |
| YfjB | - |
Escherichia coli |
| YjbN | - |
Bacillus subtilis |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Glycine max | low downregulation by heat stress | down |
| Arabidopsis thaliana | moderate downregulation by cold stress | down |
| Solanum lycopersicum | moderate downregulation by drought stress and heat stress | down |
| Glycine max | moderate downregulation by heat stress | down |
| Arabidopsis thaliana | high upregulation by drought strss and salt stress, low upregulatation by heat stress and cold stress | up |
| Glycine max | low upregulation by drought stress | up |
| Arabidopsis thaliana | low upregulation by salt stress, moderate upregulatation by heat stress | up |
| Glycine max | moderate upregulation by drought stress | up |
| Glycine max | moderate upregulation by drought stress and low upregulation by heat stress | up |
| Solanum lycopersicum | moderate upregulation by salt stress | up |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
