Literature summary for 2.7.1.22 extracted from

Belenky, P.; Racette, F.G.; Bogan, K.L.; McClure, J.M.; Smith, J.S.; Brenner, C.
Nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+ (2007), Cell, 129, 473-484.

Search for more literature for 2.7.1.22

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + N-ribosylnicotinamide	Saccharomyces cerevisiae	nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+	ADP + nicotinamide ribonucleotide	-	?

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	P53915	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + N-ribosylnicotinamide	nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+	Saccharomyces cerevisiae	ADP + nicotinamide ribonucleotide	-	?

Synonyms

Synonyms	Comment	Organism
nicotinamide riboside kinase	-	Saccharomyces cerevisiae
Nrk	-	Saccharomyces cerevisiae

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Release 2023.1 (January 2023)