Application | Comment | Organism |
---|---|---|
medicine | the thymidine kinase 1 gene from tomato in combination with azidothymidine is a powerful suicide gene for anticancer gene therapy | Solanum lycopersicum |
Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli KY895 cells | Solanum lycopersicum |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
25600 | - |
2 * 25600, calculated from amino acid sequence | Solanum lycopersicum |
38000 | - |
thymidine kinase 1 without ATP, gel filtration | Solanum lycopersicum |
59000 | - |
thymidine kinase 1 with ATP, gel filtration | Solanum lycopersicum |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Solanum lycopersicum | Q71F77 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + azidothymidine | - |
Solanum lycopersicum | ? | - |
? | |
ATP + azidothymidine monophosphate | - |
Solanum lycopersicum | ? | - |
? | |
ATP + thymidine | - |
Solanum lycopersicum | ADP + dTMP | - |
? |
Subunits | Comment | Organism |
---|---|---|
homodimer | 2 * 25600, calculated from amino acid sequence | Solanum lycopersicum |
Synonyms | Comment | Organism |
---|---|---|
thymidine kinase 1 | - |
Solanum lycopersicum |
TK1 | - |
Solanum lycopersicum |