Inhibitors | Comment | Organism | Structure |
---|---|---|---|
dCTP | 80% inhibition of adult enzyme at 1 mM, almost no inhibition of fetal enzyme | Homo sapiens | |
dTMP | - |
Homo sapiens | |
dTTP | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Homo sapiens | 5829 | - |
mitochondrion | - |
Homo sapiens | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial | Homo sapiens |
rLyTK1Val-106 and rLyTK1Met-106 | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
fetus | - |
Homo sapiens | - |
liver | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Homo sapiens |
Storage Stability | Organism |
---|---|
-20°C, 50% glycerol, relatively stable | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + thymidine | ATP can be substituted by dATP | Homo sapiens | ADP + dTMP | - |
? |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
45 | - |
5 min, fetal liver: 50% loss of activity, adult liver: 10% loss of activity | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | 8.5 | adult liver | Homo sapiens |
7 | 7.2 | fetal liver | Homo sapiens |