Literature summary for 2.7.1.20 extracted from

Kim, Y.A.; Sharon, A.; Chu, C.K.; Rais, R.H.; Al Safarjalani, O.N.; Naguib, F.N.; el Kouni, M.H.
Structure-activity relationships of 7-deaza-6-benzylthioinosine analogues as ligands of Toxoplasma gondii adenosine kinase (2008), J. Med. Chem., 51, 3934-3945.

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Inhibitors

Inhibitors	Comment	Organism	Structure
adenosine	-	Toxoplasma gondii
pyrimethamine	-	Toxoplasma gondii
Sulfadiazine	-	Toxoplasma gondii

Organism

Organism	UniProt	Comment	Textmining
Toxoplasma gondii	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + adenosine	-	Toxoplasma gondii	ADP + AMP	-	?

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.0089	-	adenosine	-	Toxoplasma gondii

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.0059	-	-	Toxoplasma gondii	pyrimethamine
0.0412	-	-	Toxoplasma gondii	Sulfadiazine

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Release 2023.1 (January 2023)