Cloned (Comment) | Organism |
---|---|
gene lsrK | Escherichia coli |
Protein Variants | Comment | Organism |
---|---|---|
additional information | genomic deletion of gene lsrK. Genes lsrK and lsrR knockouts behave identically concerning the quantity and architecture of biofilms by affecting genes including flu and wza, small riboregulators respond to the QS regulators lsrR and lsrK, e.g. the sRNA cell division inhibitor DicF is induced by at least twofold in both lsrR and lsrK mutants. 117 and 32 genes are induced and repressed, respectively, by lsrK, transcriptosome analysis in enzyme mutants, overview | Escherichia coli |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + autoinducer-2 | Escherichia coli | i.e. AI-2 | ADP + phosphorylated autoinducer-2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
W3110, gene lsrK | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + autoinducer-2 | i.e. AI-2 | Escherichia coli | ADP + phosphorylated autoinducer-2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
lsrK | - |
Escherichia coli |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Escherichia coli |
General Information | Comment | Organism |
---|---|---|
malfunction | deletion of lsrR and lsrK does not affect growth or motility. Genomic deletion of gene lsrK. Genes lsrK and lsrR knockouts behave identically concerning the quantity and architecture of biofilms by affecting genes including flu and wza, small riboregulators respond to the QS regulators lsrR and lsrK | Escherichia coli |
metabolism | the regulatory network for the uptake of Escherichia coli autoinducer 2 (AI-2) is comprised of a transporter complex, LsrABCD, its repressor, LsrR, and the cognate signal kinase, LsrK. This network is an integral part of the AI-2 quorum-sensing system, extended model for AI-2 signaling, overview | Escherichia coli |
physiological function | repressor LsrR and kinase LsrK directly regulate autoinducer 2, AI-2, uptake. Small riboregulators respond to the QS regulators lsrR and lsrK. 117 and 32 genes are induced and repressed, respectively, by lsrK | Escherichia coli |