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Literature summary for 2.7.1.153 extracted from

  • Cammer, M.; Gevrey, J.C.; Lorenz, M.; Dovas, A.; Condeelis, J.; Cox, D.
    The mechanism of CSF-1-induced Wiskott-Aldrich syndrome protein activation in vivo: a role for phosphatidylinositol 3-kinase and Cdc42 (2009), J. Biol. Chem., 284, 23302-23311.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens
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General Information

General Information Comment Organism
metabolism WASP activation downstream of CSF-1R is phosphatidylinositol 3-kinase- and Cdc42-dependent consistent with an involvement of these molecules in macrophage migration, regulation, overview Homo sapiens
physiological function the enzyme plays a pivotal role in the mechanism of CSF-1-induced Wiskott-Aldrich syndrome protein activation in vivo Homo sapiens