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Literature summary for 2.7.1.153 extracted from

  • Liu, L.; Puri, K.D.; Penninger, J.M.; Kubes, P.
    Leukocyte PI3Kgamma and PI3Kdelta have temporally distinct roles for leukocyte recruitment in vivo (2007), Blood, 110, 1191-1198.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus PI3Kgamma plays an important role in neutrophil emigration but not rolling and limited adhesion in postcapillary venules in vivo. The leukocyte but not the endothelial PI3Kgamma is critically involved in the early neutrophil emigration into the inflamed tissues. The delayed neutrophil emigration in response to neutrophil chemokines is independent of the function of PI3Lgamma but is PI3Kdelta dependent ?
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additional information Mus musculus the delayed neutrophil emigration in response to neutrophil chemokines is independent of the function of PI3Lgamma but is PI3Kdelta dependent ?
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?

Organism

Organism UniProt Comment Textmining
Mus musculus O35904
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Mus musculus Q9JHG7
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Source Tissue

Source Tissue Comment Organism Textmining
endothelium PI3Kgamma Mus musculus
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leukocyte PI3Kgamma Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information PI3Kgamma plays an important role in neutrophil emigration but not rolling and limited adhesion in postcapillary venules in vivo. The leukocyte but not the endothelial PI3Kgamma is critically involved in the early neutrophil emigration into the inflamed tissues. The delayed neutrophil emigration in response to neutrophil chemokines is independent of the function of PI3Lgamma but is PI3Kdelta dependent Mus musculus ?
-
?
additional information the delayed neutrophil emigration in response to neutrophil chemokines is independent of the function of PI3Lgamma but is PI3Kdelta dependent Mus musculus ?
-
?

Synonyms

Synonyms Comment Organism
PI3Kdelta
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Mus musculus
PI3Kgamma
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Mus musculus