Inhibitors | Comment | Organism | Structure |
---|---|---|---|
inositol(1,3,4)-trisphosphate | potently inhibits hITPK1 activity towards insositol (3,4,5,6)-tetrakisphosphate, IC50: 0.0076 mM | Homo sapiens | |
inositol(3,5,6)-trisphosphate | IC50: 0.1 mM | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00018 | - |
inositol (1,4,5,6)-tetrakisphosphate | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | inositol (1,4,5,6)-tetrakisphosphate is not a physiological substrate | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
recombinant | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
inositol (1,4,5,6)-tetrakisphosphate + ATP | hITPK1 has more than 13000fold preference for inositol (3,4,5,6)-tetrakisphosphate over its enantiomer inositol (1,4,5,6)-tetrakisphosphate | Homo sapiens | inositol (1,3,4,5,6)-pentakisphosphate + ADP | - |
? | |
inositol (3,4,5,6)-tetrakisphosphate + ATP | hITPK1 has more than 13000fold preference for inositol (3,4,5,6)-tetrakisphosphate over its enantiomer inositol (1,4,5,6)-tetrakisphosphate | Homo sapiens | inositol (1,3,4,5,6)-pentakisphosphate + ADP | - |
? | |
additional information | inositol (1,4,5,6)-tetrakisphosphate is not a physiological substrate | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ITPK1 | - |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00015 | - |
inositol (1,3,4)-trisphosphate | - |
Homo sapiens | |
0.002 | - |
inositol (3,5,6)-trisphosphate | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0076 | - |
potently inhibits hITPK1 activity towards insositol (3,4,5,6)-tetrakisphosphate, IC50: 0.0076 mM | Homo sapiens | inositol(1,3,4)-trisphosphate | |
0.1 | - |
IC50: 0.1 mM | Homo sapiens | inositol(3,5,6)-trisphosphate |