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Literature summary for 2.7.1.15 extracted from

  • Ogbunude, P.O.; Lamour, N.; Barrett, M.P.
    Molecular cloning, expression and characterization of ribokinase of Leishmania major (2007), Acta Biochim. Biophys. Sin. (Shanghai), 39, 462-466.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
overexpression in Escherichia coli Leishmania major

Inhibitors

Inhibitors Comment Organism Structure
D-ribose 5-phosphate inhibits the phosphorylation of D-ribose Leishmania major

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.2
-
ATP
-
Leishmania major
0.3
-
D-ribose
-
Leishmania major

Organism

Organism UniProt Comment Textmining
Leishmania major
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + D-ribose
-
Leishmania major ADP + D-ribose 5-phosphate
-
?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
10.2
-
ATP
-
Leishmania major
10.8
-
D-ribose
-
Leishmania major

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.4
-
D-ribose 5-phosphate
-
Leishmania major