Protein Variants | Comment | Organism |
---|---|---|
additional information | PI 3-kinase activity is not affected by Nrf2 knockdown. Overexpression of DELTAp85 inhibits the enzyme | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
LY294002 | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
muscle | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
PI 3-kinase | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | involvement of PI 3-kinase in the Nrf2 pathway during muscle differentiation. Nrf2 is transcriptionally up-regulated and translocated to the nucleus during myogenesis, but does not affect the PI 3-kinase activity acting downstream of it, overview | Homo sapiens |