Literature summary for 2.7.1.137 extracted from

Mitchell, C.; Kabolizadeh, P.; Ryan, J.; Roberts, J.D.; Yacoub, A.; Curiel, D.T.; Fisher, P.B.; Hagan, M.P.; Farrell, N.P.; Grant, S.; Dent, P.
Low-dose BBR3610 toxicity in colon cancer cells is p53-independent and enhanced by inhibition of epidermal growth factor receptor (ERBB1)-phosphatidyl inositol 3 kinase signaling (2007), Mol. Pharmacol., 72, 704-714.

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Inhibitors

Inhibitors	Comment	Organism	Structure
Ly-294002	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
colonic adenocarcinoma cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + 1-phosphatidylinositol	-	Homo sapiens	ADP + phosphatidylinositol 3-phosphate	-	?

Synonyms

Synonyms	Comment	Organism
phosphatidyl-inositol-3-kinase	-	Homo sapiens
PI3K	-	Homo sapiens

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Release 2023.1 (January 2023)