Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.1.114 extracted from

  • Falke, D.; Nehrbass, W.; Brauer, D.; Müller, W.E.G.
    Adenylic acid: deoxythymidine 5-phosphotransferase: evidence for the existence of a novel Herpes simplex virus-induced enzyme (1981), J. Gen. Virol., 53, 247-255.
    View publication on PubMed
Search for more literature for 2.7.1.114

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0021
-
 thymidine 37°C, pH 7.8 Herpes simplex virus
0.0023
-
 AMP 37°C, pH 7.8 Herpes simplex virus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
90600 111000 glycerol density gradient centrifugation Herpes simplex virus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
AMP + thymidine Herpes simplex virus
-
 adenosine + dTMP
-
 ?

Organism

Organism UniProt Comment Textmining
Herpes simplex virus
-
 type 1
-
Herpes simplex virus
-
 hamster BHK cells infected with virus
-

Purification (Commentary)

Purification (Comment) Organism
type 1, hamster BHK-cells infected with virus Herpes simplex virus

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
42.2
-
-
 Herpes simplex virus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
AMP + thymidine
-
 Herpes simplex virus adenosine + dTMP
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37 38
-
 Herpes simplex virus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.6
-
-
 Herpes simplex virus

pH Range

pH Minimum pH Maximum Comment Organism
6.3 8.8 17% of maximal activity at pH 6.3, 32% of maximal activity at pH 8.8 Herpes simplex virus