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Literature summary for 2.7.1.11 extracted from
- Phosphofructokinase-1 subunit composition and activity in the skeletal muscle, liver, and brain of dogs (2019), J. Vet. Med. Sci., 81, 712-716 .
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 78000 | - |
SDS-PAGE | Canis lupus familiaris |
| 85000 | - |
SDS-PAGE | Canis lupus familiaris |
| 86000 | - |
SDS-PAGE | Canis lupus familiaris |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + D-fructose 6-phosphate | Canis lupus familiaris | key regulatory enzyme of glycolysis | ADP + D-fructose 1,6-bisphosphate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Canis lupus familiaris | - |
- |
- |
| Canis lupus familiaris | F1Q3S9 | - |
- |
| Canis lupus familiaris | P52784 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | expression of phosphofructokinase-M, -L, and -P | Canis lupus familiaris | - |
| liver | expressed mainly phosphofructokinase-L | Canis lupus familiaris | - |
| skeletal muscle | expresses only phosphofructokinase-M | Canis lupus familiaris | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + D-fructose 6-phosphate | - |
Canis lupus familiaris | ADP + D-fructose 1,6-bisphosphate | - |
? | |
| ATP + D-fructose 6-phosphate | key regulatory enzyme of glycolysis | Canis lupus familiaris | ADP + D-fructose 1,6-bisphosphate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 78000, SDS-PAGE | Canis lupus familiaris |
| ? | x * 86000, SDS-PAGE | Canis lupus familiaris |
| ? | x * 85000, SDS-PAGE | Canis lupus familiaris |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PFK-1 | - |
Canis lupus familiaris |
| PFK-L | - |
Canis lupus familiaris |
| PFK-M | - |
Canis lupus familiaris |
| PFK-P | - |
Canis lupus familiaris |
| phosphofructokinase-1 | - |
Canis lupus familiaris |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 25 | - |
assay at | Canis lupus familiaris |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.2 | - |
assay at | Canis lupus familiaris |
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Release 2023.1 (January 2023)
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