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Literature summary for 2.7.1.11 extracted from

  • Russell, P.; Williams, A.; Marquez, K.; Hua, T.; Ehya, F.; Hardamon, C.; Tallman, T.; Valdez, P.
    Effect of ammonium, sodium, and potassium ions on rabbit muscle phosphofructokinase-1 and adenylate kinase activities (2009), J. Enzyme Inhib. Med. Chem., 24, 930-936.
    View publication on PubMed
Search for more literature for 2.7.1.11

Inhibitors

Inhibitors Comment Organism Structure
K+ about 30% residual activity of 30 nM PFK-1 in the presence of 0.2 M K+ Bos taurus
K+ about 30% residual activity of 30 nM PFK-1 in the presence of 0.2 M K+ Oryctolagus cuniculus
Lactate dehydrogenase lactate dehydrogenase suspended in 3.2 M ammonium sulfate inhibits 30 nM PFK-1 resulting in a more than 50% inhibition of activity Bos taurus
Lactate dehydrogenase lactate dehydrogenase suspended in 3.2 M ammonium sulfate inhibits 30 nM PFK-1 resulting in a more than 50% inhibition of activity Oryctolagus cuniculus
Na+ about 70% residual activity of 30 nM PFK-1 in the presence of 0.2 M Na+ Bos taurus
Na+ about 70% residual activity of 30 nM PFK-1 in the presence of 0.2 M Na+ Oryctolagus cuniculus
NH4+ about 40% residual activity of 30 nM PFK-1 in the presence of 0.2 M NH4+ Bos taurus
NH4+ about 40% residual activity of 30 nM PFK-1 in the presence of 0.2 M NH4+ Oryctolagus cuniculus

Metals/Ions

Metals/Ions Comment Organism Structure
additional information Na+ has little or no effect at 140 nM PFK-1 Bos taurus
additional information Na+ has little or no effect at 140 nM PFK-1 Oryctolagus cuniculus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Oryctolagus cuniculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
muscle
-
 Bos taurus
-
muscle
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + D-fructose 6-phosphate
-
 Bos taurus ADP + D-fructose 1,6-bisphosphate
-
 ?
ATP + D-fructose 6-phosphate
-
 Oryctolagus cuniculus ADP + D-fructose 1,6-bisphosphate
-
 ?

Synonyms

Synonyms Comment Organism
PFK-1
-
 Bos taurus
PFK-1
-
 Oryctolagus cuniculus
phosphofructokinase-1
-
 Bos taurus
phosphofructokinase-1
-
 Oryctolagus cuniculus

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Bos taurus
ATP
-
 Oryctolagus cuniculus