Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.1.11 extracted from

  • Nicolau, J.; Souza, D.N.; Nunez-Burgos, G.
    Regulation of phosphofructokinase-1 on submandibular salivary glands of rats after isoproterenol administration (2000), Arch. Physiol. Biochem., 108, 437-443.
    View publication on PubMed
Search for more literature for 2.7.1.11

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.01
-
 fructose 6-phosphate 12 h after isoproterenol administration Rattus norvegicus
0.06
-
 ATP PFK-1 Rattus norvegicus
0.086
-
 D-fructose 6-phosphate
-
 Rattus norvegicus
0.1
-
 ATP 12 h after isoproterenol administration, PFK-1 Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
side-chain modification 4.2 mol phosphate/mol of enzyme in rats treated with 3 doses of isoproterenol, 3 mol phosphate/mol enzyme after dephosphorylation, presence of phosphate groups influences the kinetic properties of PFK-1 Rattus norvegicus

Purification (Commentary)

Purification (Comment) Organism
DEAE Sepharose, Affi-gel blue Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
submandibular gland
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 slight increase in rats 12 h after isoproterenol administration Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + D-fructose 6-phosphate
-
 Rattus norvegicus ADP + D-fructose 1,6-bisphosphate
-
 ?