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Literature summary for 2.7.1.11 extracted from
- Purification and kinetic properties of phosphofructokinase from dental pulps of rat incisors (1985), Arch. Oral Biol., 30, 577-582.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| ATP | pH-dependent inhibition | Rattus norvegicus |  |
| citrate | at pH 7.6, not at pH 8.4 | Rattus norvegicus | |
| additional information | not inhibited by fructose 6-phosphate | Rattus norvegicus | |
| phosphoenolpyruvate | at pH 7.6, not at pH 8.4 | Rattus norvegicus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.05 | - |
ATP | pH 8.4 | Rattus norvegicus | |
| 0.18 | - |
D-fructose 6-phosphate | pH 8.4 | Rattus norvegicus | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | required for activity | Rattus norvegicus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| ammonium sulfate, phenyl-Sepharose | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| dental pulp | incisor | Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + D-fructose 6-phosphate | - |
Rattus norvegicus | ADP + D-fructose 1,6-bisphosphate | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.4 | - |
- |
Rattus norvegicus |
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