Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | isoform diacylglycerol kinase delta-1, but not a splice variant isoform diacylglycerol kinase delta-2 or the other type II isoform diacylglycerol kinase ny-1/2, translocates from the cytoplasm to the plasma membrane in HEK-293 and mouse myoblast C2C12 cells within 5 min in response to high glucose levels. The translocation is inhibited by phosphatidylinositol 3-kinase inhibitors, LY294002 and GDC-0941. The PH and C1 domains are responsible for the plasma membrane translocation and the sterile alpha-motif domain negatively regulates the translocation | Homo sapiens | 5737 | - |
plasma membrane | isoform diacylglycerol kinase delta-1, but not a splice variant isoform diacylglycerol kinase delta-2 or the other type II isoform diacylglycerol kinase ny-1/2, translocates from the cytoplasm to the plasma membrane in HEK-293 and mouse myoblast C2C12 cells within 5 min in response to high glucose levels. The translocation is inhibited by phosphatidylinositol 3-kinase inhibitors, LY294002 and GDC-0941. The PH and C1 domains are responsible for the plasma membrane translocation and the sterile alpha-motif domain negatively regulates the translocation | Homo sapiens | 5886 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q16760 | isoform diacylglycerol kinase delta | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HEK-293 cell | - |
Homo sapiens | - |