Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | O08560 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
microglia | DGKzeta-immunoreactivity is clearly detected in Iba1-immunoreactive cells of an oval or ameboid shape in the scar region, which represent activated microglia and/or macrophages. DGKzeta-immunoreactivity is not detected in Iba1-immunoreactive, resting microglia of ramified and dendritic configuration in the intact cortex | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 1,2-diacylglycerol | - |
Rattus norvegicus | ADP + 1,2-diacyl-sn-glycerol 3-phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DGKzeta | - |
Rattus norvegicus |
diacylglycerol kinase zeta | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Rattus norvegicus |
Organism | Comment | Expression |
---|---|---|
Rattus norvegicus | as early as 1h after cryoinjury, DGKzeta-immunoreactivity is greatly decreased in the afflicted cerebral cortex and almost disappears in the necrotic core. On day 7 after cryoinjury, however, DGKzeta-immunoreactivity reappears in this area | down |
Rattus norvegicus | DGKzeta is induced in activated microglia in brain trauma | up |