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Literature summary for 2.7.1.107 extracted from

  • Nakano, T.; Hozumi, Y.; Goto, K.; Wakabayashi, I.
    Localization of diacylglycerol kinase epsilon on stress fibers in vascular smooth muscle cells (2009), Cell Tissue Res., 337, 167-175.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
actin filament DGKepsilon is detected in a filamentous pattern, parallel to the long axis of cell, and on actin stress fibers Rattus norvegicus 5884
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cytoplasm isoform DGKalpha is detected sparsely in the cytoplasm, in aortic smooth muscle cell contracted by serotonin DGKepsilon is detected diffusely in the cytoplasm without a filamentous stress fiber pattern Rattus norvegicus 5737
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nucleus isoform DGKzeta is observed as a granular pattern in the nucleus, isoform DGKalpha is detected sparsely in the nucleus Rattus norvegicus 5634
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Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
A7r5 cell
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Rattus norvegicus
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aortic smooth muscle cell
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Rattus norvegicus
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vascular smooth muscle cell
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Rattus norvegicus
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Synonyms

Synonyms Comment Organism
DGKalpha isoform Rattus norvegicus
DGKepsilon isoform Rattus norvegicus
DGKzeta isoform Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
ATP
-
Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus protein and mRNA expression of isoform DGKepsilon in aortic smooth muscle cells is significantly increased by stimulation with serotonin up

General Information

General Information Comment Organism
physiological function isoform DGKepsilon interacts with actin stress fibers and is involved in their stability in vascular smooth muscle cells Rattus norvegicus