Literature summary for 2.7.1.107 extracted from

Kobayashi, N.; Hozumi, Y.; Ito, T.; Hosoya, T.; Kondo, H.; Goto, K.
Differential subcellular targeting and activity-dependent subcellular localization of diacylglycerol kinase isozymes in transfected cells (2007), Eur. J. Cell Biol., 86, 433-444.

Search for more literature for 2.7.1.107

Cloned(Commentary)

Cloned (Comment)	Organism
expression in COS-7 cell	Rattus norvegicus

Protein Variants

Protein Variants	Comment	Organism
G279D	inactive mutant of diacylglycerol kinase epsilon due to replacement of ATP-binding domain GxGxxG with GxDxxG. Similar subcellular localization as wild type	Rattus norvegicus
G356D	inactive mutant of diacylglycerol kinase zeta due to replacement of ATP-binding domain GxGxxG with GxDxxG. Similar subcellular localization as wild type	Rattus norvegicus
G428D	inactive mutant of diacylglycerol kinase alpha due to replacement of ATP-binding domain GxGxxG with GxDxxG. Similar subcellular localization as wild type	Rattus norvegicus
G491D	inactive mutant of diacylglycerol kinase gamma due to replacement of ATP-binding domain GxGxxG with GxDxxG. Similar subcellular localization as wild type	Rattus norvegicus
G495D	inactive mutant of diacylglycerol kinase beta due to replacement of ATP-binding domain GxGxxG with GxDxxG. In contrast to the filamentous image of the wild type, mutant is diffusely distributed throughout the cytoplasm	Rattus norvegicus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytoplasm	-	Rattus norvegicus	5737	-
cytoplasm	co-localizes with actin filaments	Rattus norvegicus	5737	-
Golgi apparatus	diacylglacerol kinase isoform gamma	Rattus norvegicus	5794	-
additional information	diacylglacerol kinase isoform epsilon is distributed around the perinuclear region	Rattus norvegicus	-	-
nucleus	-	Rattus norvegicus	5634	-

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	isoforms gamma, epsilon	-
Rattus norvegicus	O08560	isoform zeta	-
Rattus norvegicus	P49621	isoform beta	-
Rattus norvegicus	P51556	isoform alpha	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Rattus norvegicus	-

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Release 2023.1 (January 2023)