Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | diacylglycerol kinase zeta and syntrophins play a role at multiple stages of the cell fusion process. Potential link between changes in the lipid content of the membranebilayer and reorganization of the actin cytoskeleton during myoblast fusion | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q80UP3 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
C2C12 cell | diacylglycerol kinase zeta and syntrophins, scaffold proteins of the dystrophin glycoprotein complex that bind directly to diacylglycerol kinase zeta, are spatially regulated during fusion of cultured cells. Both proteins accumulate with the GTPase Rac1 at sites where fine filopodia mediate the initial contact between myoblasts. Diacylglycerol kinase zeta codistributes with the Ca2+-dependent cell adhesion molecule N-cadherin at nascent cell contacts | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | diacylglycerol kinase zeta and syntrophins play a role at multiple stages of the cell fusion process. Potential link between changes in the lipid content of the membranebilayer and reorganization of the actin cytoskeleton during myoblast fusion | Mus musculus | ? | - |
? |