Activating Compound | Comment | Organism | Structure |
---|---|---|---|
H2O2 | endogenous nuclear diacylglycerol kinase zeta rapidly translocates to the cytoplasm following H2O2 treatment | Rattus norvegicus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | diacylglycerol kinase zeta siRNA tranfection decreases H2O2-induced apoptosis. Overexpression of kinase-dead diacylglycerol kinase zeta significantly increases protein kinase D phosphorylation | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
H2O2 | endogenous nuclear diacylglycerol kinase zeta rapidly translocates to the cytoplasm following H2O2 treatment | Rattus norvegicus | |
R59022 | inhibition of diacylglycerol kinase decreases H2O2-induced RIE-1 cell apoptosis | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | diacylglycerol kinase is involved in the regulation of oxidative stress-induced intestinal cell injury | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
IEC-6 cell | - |
Rattus norvegicus | - |
RIE-1 cell | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | diacylglycerol kinase is involved in the regulation of oxidative stress-induced intestinal cell injury | Rattus norvegicus | ? | - |
? |