Inhibitors | Comment | Organism | Structure |
---|---|---|---|
R59022 | specifc inhibitor of diacylglycerol kinase. Treatment significantly increases glucose transport, p38 and MKK3/6 activation in myotubes. The R59022-induced glucose transport is blocked by SB203580, a specific p38 inhibitor. R59022 fails to stimulate both possible known mechanisms to enhance glucose transport, an IRS1-PI3K-Akt pathway, muscle contraction signaling or GLUT1 and GLUT4 expression | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
C2C12 cell | - |
Mus musculus | - |
myotube | expression of diacylglycerol kinase isoform alpha, delta, epsilon, zeta, or theta mRNA | Mus musculus | - |