Literature summary for 2.7.1.107 extracted from

Cipres, A.; Carrasco, S.; Merino, E.; Diaz, E.; Krishna, U.M.; Falck, J.R.; Martinez-A, C.; Merida, I.
Regulation of Diacylglycerol Kinase a by Phosphoinositide 3-Kinase Lipid Products (2003), J. Biol. Chem., 278, 35629-35635.

Search for more literature for 2.7.1.107

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
plasma membrane	activation and relocalization to plasma membrane of DGKalpha is a direct consequence of PI3K activation	Mus musculus	5886	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + 1,2-diacyl-sn-glycerol	Mus musculus	DAGKalpha is stimulated vby Src-like kinase-dependent phosphoinositide 3 kinase activation in lymphocytes. In vivo the increase in cellular levels of Src-like kinase-dependent phosphoinositide 3 kinase products is sufficient to induce DAGKalpha activation, allowing DAGKalpha relocation to the intact lymphocyte	ADP + 1,2-diacyl-sn-glycerol 3-phosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
lymphocyte	-	Mus musculus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + 1,2-diacyl-sn-glycerol	DAGKalpha is stimulated vby Src-like kinase-dependent phosphoinositide 3 kinase activation in lymphocytes. In vivo the increase in cellular levels of Src-like kinase-dependent phosphoinositide 3 kinase products is sufficient to induce DAGKalpha activation, allowing DAGKalpha relocation to the intact lymphocyte	Mus musculus	ADP + 1,2-diacyl-sn-glycerol 3-phosphate	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)