Cloned (Comment) | Organism |
---|---|
COS-7 cells transfected with DGKksi cDNA express a 117000 Da and a 114000 Da protein. The transfected cells also express increased diacylglycerol kinase activity, which is not altered in the presence of R59949 | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zinc | the enzyme contains two zinc fingers | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
103900 | - |
x * 103900, calculation from nucleotide sequence | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q13574 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | DGKksi mRNA is expressed at high level | Homo sapiens | - |
endothelium | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 1,2-dicapryl-sn-glycerol | about 140% of the activity with sn-1,2-dioleoylglycerol | Homo sapiens | ADP + 1,2-dicapryl-sn-glycerol 3-phosphate | - |
? | |
ATP + 1-oleoyl-2-palmitoyl-sn-glycerol | about 85% of the activity with sn-1,2-dioleoylglycerol, DGKksi | Homo sapiens | ADP + 1-palmitoyl-2-oleoyl-sn-glycerol 3-phosphate | - |
? | |
ATP + 1-palmitoyl-2-oleoyl-sn-glycerol | about 80% of the activity with sn-1,2-dioleoylglycerol | Homo sapiens | ADP + 1-palmitoyl-2-oleoyl-sn-glycerol 3-phosphate | - |
? | |
ATP + 1-palmitoyl-2-oleoyl-sn-glycerol | about 80% of the activity with sn-1,2-dioleoylglycerol, DGKksi | Homo sapiens | ADP + 1-palmitoyl-2-oleoyl-sn-glycerol 3-phosphate | - |
? | |
ATP + 1-stearoyl-2-arachidonoyl-sn-glycerol | 108% of the activity with sn-1,2-dioleoylglycerol | Homo sapiens | ADP + 1-stearoyl-2-arachidonoyl-sn-glycerol 3-phosphate | - |
? | |
ATP + sn-1,2-dioleoylglycerol | recombinant DGKksi | Homo sapiens | ADP + sn-1,2-dioleoylglycerol 3-phosphate | - |
? | |
ATP + sn-1,3-dioleoylglycerol | about 10% of the activity with sn-1,2-dioleoylglycerol | Homo sapiens | ADP + ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 103900, calculation from nucleotide sequence | Homo sapiens |