BRENDA - Enzyme Database show
show all sequences of 2.7.1.106

Molecular identification of mammalian phosphopentomutase and glucose-1,6-bisphosphate synthase, two members of the alpha-D-phosphohexomutase family

Maliekal, P.; Sokolova, T.; Vertommen, D.; Veiga-da-Cunha, M.; Van Schaftingen, E.; J. Biol. Chem. 282, 31844-31851 (2007)

Data extracted from this reference:

Cloned(Commentary)
Commentary
Organism
expression in Escherichia coli as fusion protein with a polyHis tag at their N-terminus
Homo sapiens
Inhibitors
Inhibitors
Commentary
Organism
Structure
2,3-bisphosphoglycerate
0.2 mM, strong inhibitor
Homo sapiens
D-Glucose 1,6-bisphosphate
0.01 mM, 50% inhibition
Homo sapiens
glycerol 3-phosphate
; 0.2 mM, strong inhibitor
Homo sapiens
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Homo sapiens
-
-
-
Purification (Commentary)
Commentary
Organism
-
Homo sapiens
Source Tissue
Source Tissue
Commentary
Organism
Textmining
brain
-
Homo sapiens
-
erythrocyte
-
Homo sapiens
-
Cloned(Commentary) (protein specific)
Commentary
Organism
expression in Escherichia coli as fusion protein with a polyHis tag at their N-terminus
Homo sapiens
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
2,3-bisphosphoglycerate
0.2 mM, strong inhibitor
Homo sapiens
D-Glucose 1,6-bisphosphate
0.01 mM, 50% inhibition
Homo sapiens
glycerol 3-phosphate
; 0.2 mM, strong inhibitor
Homo sapiens
Purification (Commentary) (protein specific)
Commentary
Organism
-
Homo sapiens
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
brain
-
Homo sapiens
-
erythrocyte
-
Homo sapiens
-
Other publictions for EC 2.7.1.106
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
674867
Maliekal
Molecular identification of ma ...
Homo sapiens
J. Biol. Chem.
282
31844-31851
2007
-
-
1
-
-
-
3
-
-
-
-
-
-
3
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
1
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
640349
Ueda
Regulation of glucose 1,6-bisp ...
Bos taurus
J. Biochem.
83
1721-1730
1978
-
-
-
-
-
-
3
8
1
1
-
1
-
1
-
-
1
-
-
2
2
-
6
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
8
1
1
-
1
-
-
-
1
-
2
2
-
6
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
640350
Rose
Inhibitors of glucose-1,6-bisp ...
Bos taurus
J. Biol. Chem.
252
4262-4268
1977
-
-
-
-
-
-
16
3
-
3
-
-
-
1
-
-
-
-
-
1
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
16
-
3
-
3
-
-
-
-
-
-
-
1
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
640348
Rose
A specific enzyme for glucose ...
Mus musculus
J. Biol. Chem.
250
3466-3470
1975
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-
-
-
-
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8
-
1
7
-
1
-
1
-
-
1
-
-
1
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-
7
-
1
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
8
-
-
1
7
-
1
-
-
-
1
-
1
-
-
7
-
1
-
-
-
1
1
-
-
-
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-
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-
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