Literature summary for 2.7.1.1 extracted from

Li, M.; Gao, Z.; Wang, Y.; Wang, H.; Zhang, S.
Identification, expression and bioactivity of hexokinase in amphioxus: insights into evolution of vertebrate hexokinase genes (2014), Gene, 535, 318-326.

Search for more literature for 2.7.1.1

Organism

Organism	UniProt	Comment	Textmining
Branchiostoma japonicum	V5KAK3	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
hepatic cecum	most abundant expression in hepatic cecum, testis and ovary	Branchiostoma japonicum	-
ovary	most abundant expression in hepatic cecum, testis and ovary	Branchiostoma japonicum	-
testis	most abundant expression in hepatic cecum, testis and ovary	Branchiostoma japonicum	-

General Information

General Information	Comment	Organism
physiological function	Branchiostoma japonicum hexokinase is the archetype of vertebrate hexokinases IV, i.e. glucokinases. Recombinant enzyme shows functional enzyme activity resembling vertebrate hexokinases I, II, III and IV. Glucokinase activity in the hepatic caecum is markedly reduced by fasting,whereas it is considerably increased by feeding. The enzyme represents the archetype of glucokinases, from which vertebrate hexokinase gene family has evolved by gene duplication, and the hepatic caecum plays a role in the control of glucose homeostasis in amphioxus	Branchiostoma japonicum

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Release 2023.1 (January 2023)