Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.1.1 extracted from

  • Claeyssen, E.; Dorion, S.; Clendenning, A.; He, J.Z.; Wally, O.; Chen, J.; Auslender, E.L.; Moisan, M.C.; Jolicoeur, M.; Rivoal, J.
    The futile cycling of hexose phosphates could account for the fact that hexokinase exerts a high control on glucose phosphorylation but not on glycolytic rate in transgenic potato (Solanum tuberosum) roots (2013), PLoS ONE, 8, e53898.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Solanum tuberosum
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
root
-
Solanum tuberosum
-

Synonyms

Synonyms Comment Organism
hexokinase
-
Solanum tuberosum

General Information

General Information Comment Organism
malfunction transgenic Solanum tuberosum roots are altered in their hexokinase activity by transformation with an hexokinase cDNA in sense or antisense orientation. Altering root hexokinase activity levels impacts on growth rate and hexokinase has a high flux control coefficient over glucose phosphorylation but does not control glycolytic flux or respiration rate. It is concluded that futile cycling of hexose-phosphate can be partially responsible for the differences in energetic status in roots with high and low hexokinase activity and possibly cause the observed alterations in growth in transgenic roots Solanum tuberosum