Literature summary for 2.7.1.1 extracted from

Kim, W.; Yoon, J.H.; Jeong, J.M.; Cheon, G.J.; Lee, T.S.; Yang, J.I.; Park, S.C.; Lee, H.S.
Apoptosis-inducing antitumor efficacy of hexokinase II inhibitor in hepatocellular carcinoma (2007), Mol. Cancer Ther., 6, 2554-2562.

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Application

Application	Comment	Organism
medicine	HK II inhibitors may be therapeutically useful for the treatment of advanced infiltrative hypovascular hepatocellular carcinomas, which are growing in a hypoxic environment	Mus musculus

Inhibitors

Inhibitors	Comment	Organism	Structure
3-Bromopyruvate	in mice treated with 3-bromopyruvate, mean tumor volumes and tumor volume growth are significantly reduced	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	C3H mice implanted with MH134 cells	-

Synonyms

Synonyms	Comment	Organism
hexokinase II	-	Mus musculus
HK II	-	Mus musculus

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Release 2023.1 (January 2023)