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Literature summary for 2.6.1.85 extracted from

  • Xie, W.; Perry, G.; Martin, C.J.; Shim, Y.-S.; Navabi, A.; Pauls, K.P.
    Molecular characterization of dihydroneopterin aldolase and aminodeoxychorismate synthase in common bean - genes coding for enzymes in the folate synthesis pathway (2017), Genome, 60, 588-600 .
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
gene ADCS, a ADCS gene-specific marker is developed, mapped and compared to its physical location on chromosome 7, DNA and amino acid sequence determination and analysis, genotyping, sequence comparisons and phylogenetic analysis Phaseolus vulgaris
gene ADCS, a ADCS gene-specific marker is developed, mapped, and compared to its physical location on chromosome 7, DNA and amino acid sequence determination and analysis, genotyping, sequence comparisons and phylogenetic analysis Phaseolus vulgaris

Protein Variants

Protein Variants Comment Organism
additional information a single-nucleotide polymorphism (SNP) for PvADCS is identified between the ADCS gene fragment sequences of BAT93 (JN392964) and Jalo EEP558 (JN392965) Phaseolus vulgaris

Organism

Organism UniProt Comment Textmining
Phaseolus vulgaris G1JT92
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Phaseolus vulgaris G1JT93
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Phaseolus vulgaris BAT93 G1JT92
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Phaseolus vulgaris Jalo EEP558 G1JT93
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Synonyms

Synonyms Comment Organism
ADC synthase
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 Phaseolus vulgaris
ADCS
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 Phaseolus vulgaris
PvADCS
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 Phaseolus vulgaris

General Information

General Information Comment Organism
evolution common beans are excellent sources of dietary folates, but different varieties contain different amounts of these compounds. Dihydroneopterin aldolase (DHNA, EC 4.1.2.25) and aminodeoxychorismate synthase (ADCS) genes in the folate synthesis pathway, are characterized by PCR amplification, BAC clone sequencing, and whole genome sequencing. All DHNA and ADCS genes in the Mesoamerican cultivar OAC Rex are isolated and compared with those genes in the genome of Andean genotype G19833. Both genotypes have two functional DHNA genes and one pseudogene. There is only one ADCS gene (PvADCS) identified in the bean genome and it is identical in OAC Rex and G19833. PvADCS has the conserved motifs required for catalytic activity similar to other plant ADCS homologues. Genotype and geotype mapping Phaseolus vulgaris
metabolism the enzyme is involved in the folate synthesis pathway Phaseolus vulgaris