Literature summary for 2.6.1.83 extracted from

Watanabe, N.; James, M.N.
Structural insights for the substrate recognition mechanism of LL-diaminopimelate aminotransferase (2011), Biochim. Biophys. Acta, 1814, 1528-1533.

Search for more literature for 2.6.1.83

Cloned(Commentary)

Cloned (Comment)	Organism
-	Chlamydia trachomatis
-	Arabidopsis thaliana

Crystallization (Commentary)

Crystallization (Comment)	Organism
-	Arabidopsis thaliana

Inhibitors

Inhibitors	Comment	Organism	Structure
N-[(5Z)-5-[(5-bromofuran-2-yl)methylidene]-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]acetamide	-	Arabidopsis thaliana
N-[3-(hydrazinylcarbonyl)naphthalen-2-yl]benzenesulfonamide	-	Arabidopsis thaliana

Organism

Organism	UniProt	Comment	Textmining
Arabidopsis thaliana	-	-	-
Chlamydia trachomatis	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Chlamydia trachomatis
-	Arabidopsis thaliana

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-glutamate + tetrahydrodipicolinate + H2O	-	Chlamydia trachomatis	LL-diaminopimelate + 2-oxoglutarate	-	r
L-glutamate + tetrahydrodipicolinate + H2O	slightly active (1%-2%) with meso-diaminopimelate, lysine and L-ornithine	Arabidopsis thaliana	LL-diaminopimelate + 2-oxoglutarate	-	r
LL-diaminopimelate + 2-oxoglutarate	also active (17%-21%) with lysine, L-ornithine and cystathionine	Chlamydia trachomatis	L-glutamate + tetrahydrodipicolinate + H2O	-	r
meso-diaminopimelate + 2-oxoglutarate	-	Chlamydia trachomatis	L-glutamate + tetrahydrodipicolinate + H2O	-	r

Synonyms

Synonyms	Comment	Organism
L,L-diaminopimelate aminotransferase	-	Arabidopsis thaliana
LL-diaminopimelate aminotransferase	-	Chlamydia trachomatis

Cofactor

Cofactor	Comment	Organism	Structure
pyridoxal 5'-phosphate	-	Chlamydia trachomatis
pyridoxal 5'-phosphate	-	Arabidopsis thaliana

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.005	-	pH not specified in the publication, temperature not specified in the publication	Arabidopsis thaliana	N-[3-(hydrazinylcarbonyl)naphthalen-2-yl]benzenesulfonamide
0.041	-	pH not specified in the publication, temperature not specified in the publication	Arabidopsis thaliana	N-[(5Z)-5-[(5-bromofuran-2-yl)methylidene]-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]acetamide

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Release 2023.1 (January 2023)