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Literature summary for 2.6.1.64 extracted from

  • Ricci, G.; Nardini, M.; Federici, G.; Cavallini, D.
    The transamination of L-cystathionine, L-cystine and related compounds by a bovine kidney transaminase (1986), Eur. J. Biochem., 157, 57-63.
    View publication on PubMed
Search for more literature for 2.6.1.64

General Stability

General Stability Organism
repeated freeze-thawing causes irreversible inactivation Bos taurus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1
-
 S-aminomethyl-L-cysteine pH 9.0, 37°C Bos taurus
1.4
-
 cystine pH 9.0, 37°C Bos taurus
1.9
-
 L-cystathionine pH 9.0, 37°C Bos taurus
1.9
-
 (-)Allocystathionine pH 9.0, 37°C Bos taurus
5
-
 L-Lanthionine pH 9.0, 37°C Bos taurus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
47000
-
 2 * 47000, SDS-PAGE Bos taurus
97000
-
 PAGE Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
 bovine
-

Purification (Commentary)

Purification (Comment) Organism
-
 Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Bos taurus
-

Storage Stability

Storage Stability Organism
-20°C, 30 mM phosphate buffer, pH 7.0, 1 mM mercaptoethanol, 1 mM EDTA, stable for at least 1 month Bos taurus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(-)allocystathionine + phenylpyruvate
-
 Bos taurus ? + L-phenylalanine
-
 r
DL-2,6-diaminoheptanedioate + phenylpyruvate
-
 Bos taurus 2-amino-6-oxoheptanedioate + L-phenylalanine
-
 r
DL-homoserine + phenylpyruvate
-
 Bos taurus 4-hydroxy-2-oxobutanoate + phenylalanine
-
 r
DL-penicillamine + phenylpyruvate
-
 Bos taurus 3-methyl-3-mercapto-2-oxo-butanoate + L-phenylalanine
-
 r
DL-threonine + phenylpyruvate
-
 Bos taurus 3-hydroxy-2-oxobutanoate + L-phenylalanine
-
 r
L-cystathionine + phenylpyruvate
-
 Bos taurus S-(2-oxo-2-carboxyethyl)homocysteine + L-phenylalanine
-
 r
L-cysteine + phenylpyruvate
-
 Bos taurus 3-mercapto-2-oxopropanoate + L-phenylalanine
-
 r
L-cystine + phenylpyruvate
-
 Bos taurus cystine ketimine + phenylalanine
-
 r
L-glutamine + 2-oxobutyrate
-
 Bos taurus 2-oxoglutaramate + 2-aminobutanoate
-
 r
L-glutamine + 4-methylsulfanyl-2-oxobutanoate
-
 Bos taurus 2-oxoglutaramate + L-methionine
-
 r
L-glutamine + glyoxylate
-
 Bos taurus 2-oxoglutaramate + glycine
-
 r
L-glutamine + pyruvate
-
 Bos taurus 2-oxoglutaramate + L-alanine
-
 r
L-histidine + phenylpyruvate
-
 Bos taurus 3-(1H-imidazol-4-yl)-2-oxopropanoate + L-phenylalanine
-
 r
L-homocysteine + phenylpyruvate
-
 Bos taurus 4-mercapto-2-oxobutanoate + L-phenylalanine
-
 r
L-homocystine + phenylpyruvate
-
 Bos taurus ? + L-phenylalanine
-
 r
L-lanthionine + phenylpyruvate
-
 Bos taurus 2H-1,4-thiazine-5,6-dihydro-3,5-dicarboxylic acid + L-phenylalanine
-
 r
L-leucine + phenylpyruvate
-
 Bos taurus 4-methyl-2-oxopentanoate + L-phenylalanine
-
 r
L-methionine + phenylpyruvate
-
 Bos taurus 4-methylsulfanyl-2-oxobutanoate + L-phenylalanine
-
 r
L-norleucine + phenylpyruvate
-
 Bos taurus 2-oxohexanoate + L-phenylalanine
-
 r
S-aminoethyl-L-cysteine + phenylpyruvate
-
 Bos taurus S-aminoethyl-(3-mercapto-2-oxopropanoate) + L-phenylalanine
-
 r
S-aminoethyl-L-cysteine + phenylpyruvate
-
 Bos taurus 2H-1,4-thiazine-5,6-dihydro-3-carboxylic acid + L-phenylalanine + H2O
-
 r
S-aminomethyl-L-cysteine + phenylpyruvate
-
 Bos taurus 2H-1,4-thiazine-5,6-dihydro-3-carboxylic acid + L-phenylalanine
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 47000, SDS-PAGE Bos taurus

Synonyms

Synonyms Comment Organism
EC 2.6.1.15 identical with Bos taurus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
10
-
 S-aminoethyl-L-cysteine as substrate Bos taurus

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
 Bos taurus