Any feedback?
Literature summary for 2.6.1.5 extracted from
- Concerted motion of structure and active site charge is required for tyrosine aminotransferase activity in Leishmania parasite (2020), Spectrochim. Acta A. Mol. Biomol. Spectrosc., 232, 118133 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli BL21 cells | Leishmania donovani |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-tyrosine + 2-oxoglutarate | Leishmania donovani | - |
4-hydroxyphenylpyruvate + L-glutamate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Leishmania donovani | A0A5B8TZA8 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| His tag affinity column chromatography | Leishmania donovani |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-tyrosine + 2-oxoglutarate | - |
Leishmania donovani | 4-hydroxyphenylpyruvate + L-glutamate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| L-tyrosine: 2 oxoglutarate aminotransferase | - |
Leishmania donovani |
| TAT | - |
Leishmania donovani |
| TATase | - |
Leishmania donovani |
| tyrosine aminotransferase | - |
Leishmania donovani |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
- |
Leishmania donovani |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 4 | 10 | more than 50% activity between pH 4.0 and 10.0 | Leishmania donovani |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Leishmania donovani | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
