show reference and datareference onlydata only

Biosynthesis of porphyrin precursors. Purification and characterization of mammalian L-alanine:gamma,delta-dioxovaleric acid aminotransferase

Data extracted from this reference:

Inhibitors

Commentary

Organism

Structure

2-oxoglutarate

-

Bos taurus

5-aminolevulinate

-

Bos taurus

methylglyoxal

-

Bos taurus

pyruvate

-

Bos taurus

succinate semialdehyde

-

Bos taurus

Tris-HCl

-

Bos taurus

KM Value [mM]

KM Value Maximum [mM]

Substrate

Commentary

Organism

Structure

0.24

-

4,5-Dioxopentanoate

pH 6.9, 37°C

Bos taurus

3.7

-

L-alanine

pH 6.9, 37°C

Bos taurus

Cofactor

Commentary

Organism

Structure

pyridoxal 5'-phosphate

-

Bos taurus

Cofactor

Commentary

Organism

Structure

pyridoxal 5'-phosphate

-

Bos taurus

Inhibitors

Commentary

Organism

Structure

2-oxoglutarate

-

Bos taurus

5-aminolevulinate

-

Bos taurus

methylglyoxal

-

Bos taurus

pyruvate

-

Bos taurus

succinate semialdehyde

-

Bos taurus

Tris-HCl

-

Bos taurus

KM Value [mM]

KM Value Maximum [mM]

Substrate

Commentary

Organism

Structure

0.24

-

4,5-Dioxopentanoate

pH 6.9, 37°C

Bos taurus

3.7

-

L-alanine

pH 6.9, 37°C

Bos taurus

No.

1st author

Pub Med

title

organims

journal

volume

pages

year

Activating Compound

Application

Cloned(Commentary)

Crystallization (Commentary)

Engineering

General Stability

Inhibitors

KM Value [mM]

Localization

Metals/Ions

Molecular Weight [Da]

Natural Substrates/ Products (Substrates)

Organic Solvent Stability

Organism

Oxidation Stability

Posttranslational Modification

Purification (Commentary)

Reaction

Renatured (Commentary)

Source Tissue

Specific Activity [micromol/min/mg]

Storage Stability

Substrates and Products (Substrate)

Subunits

Temperature Optimum [°C]

Temperature Range [°C]

Temperature Stability [°C]

Turnover Number [1/s]

pH Optimum

pH Range

pH Stability

Cofactor

Ki Value [mM]

pI Value

IC50 Value

Activating Compound (protein specific)

Application (protein specific)

Cloned(Commentary) (protein specific)

Cofactor (protein specific)

Crystallization (Commentary) (protein specific)

Engineering (protein specific)

General Stability (protein specific)

IC50 Value (protein specific)

Inhibitors (protein specific)

Ki Value [mM] (protein specific)

KM Value [mM] (protein specific)

Localization (protein specific)

Metals/Ions (protein specific)

Molecular Weight [Da] (protein specific)

Natural Substrates/ Products (Substrates) (protein specific)

Organic Solvent Stability (protein specific)

Oxidation Stability (protein specific)

Posttranslational Modification (protein specific)

Purification (Commentary) (protein specific)

Renatured (Commentary) (protein specific)

Source Tissue (protein specific)

Specific Activity [micromol/min/mg] (protein specific)

Storage Stability (protein specific)

Substrates and Products (Substrate) (protein specific)

Subunits (protein specific)

Temperature Optimum [°C] (protein specific)

Temperature Range [°C] (protein specific)

Temperature Stability [°C] (protein specific)

Turnover Number [1/s] (protein specific)

pH Optimum (protein specific)

pH Range (protein specific)

pH Stability (protein specific)

pI Value (protein specific)

Expression

General Information

General Information (protein specific)

Expression (protein specific)

KCat/KM [mM/s]

KCat/KM [mM/s] (protein specific)

739231

Salgueiro

Effects of Bauhinia forficata ...

Mus musculus

Oxid. Med. Cell. Longev.

2016

0000

2016

-

1

-

-

-

-

-

-

-

-

-

-

-

1

-

-

-

-

-

1

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

1

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

1

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

640064

Lombardo

5-Aminolevulinic acid synthesi ...

Trypanosoma cruzi

Int. J. Biochem. Cell Biol.

35

1263-1271

2003

-

1

-

-

-

-

-

-

-

-

-

1

-

2

-

-

-

-

-

1

-

-

1

-

-

-

-

-

-

-

-

-

-

-

-

-

1

-

-

-

-

-

-

-

-

-

-

-

-

1

-

-

-

-

-

1

-

-

1

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

640063

Sagar

L-alanine: 4,5-dioxovalerate t ...

Leishmania donovani

Microbiol. Res.

150

419-423

1995

-

1

-

-

-

-

2

1

-

-

-

1

-

1

-

-

-

-

-

-

-

-

7

-

1

-

-

-

-

-

-

-

-

-

-

-

1

-

-

-

-

-

-

2

-

1

-

-

-

1

-

-

-

-

-

-

-

-

7

-

1

-

-

-

-

-

-

-

-

-

-

-

-

-

640062

Tyagi

A rapid, high-yield purificati ...

Rattus norvegicus, Rattus norvegicus Wistar

Protein Expr. Purif.

5

527-533

1994

-

-

-

-

-

1

1

-

1

-

3

4

-

166

-

-

1

-

-

2

1

1

6

1

1

1

1

-

-

-

-

-

-

1

-

-

-

-

-

-

-

1

-

1

-

-

1

-

3

4

-

-

-

1

-

2

1

1

6

1

1

1

1

-

-

-

-

1

-

-

-

-

-

-

640061

Tyagi

In vitro translocation of L-al ...

Rattus norvegicus

J. Biochem.

113

557-562

1993

-

-

-

-

-

-

1

-

1

-

-

1

-

1

-

-

-

-

-

1

-

-

2

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

1

-

-

1

-

-

1

-

-

-

-

-

1

-

-

2

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

640059

McKinney

Production of delta-aminolevul ...

Mus musculus

Int. J. Biochem.

23

803-810

1991

-

-

-

-

-

-

7

2

-

-

-

1

-

2

-

-

-

-

-

2

-

-

1

-

-

-

-

-

1

-

-

-

-

-

-

-

-

-

-

-

-

-

-

7

-

2

-

-

-

1

-

-

-

-

-

2

-

-

1

-

-

-

-

-

1

-

-

-

-

-

-

-

-

-

640060

Singh

Cytosolic L-alanine:4,5-dioxov ...

Rattus norvegicus, Rattus norvegicus Wistar

Eur. J. Biochem.

198

581-587

1991

1

-

-

-

-

1

1

-

2

-

4

-

-

166

-

-

1

-

-

2

1

1

-

1

1

-

-

-

1

-

-

-

-

-

-

1

-

-

-

-

-

1

-

1

-

-

2

-

4

-

-

-

-

1

-

2

1

1

-

1

1

-

-

-

1

-

-

-

-

-

-

-

-

-

640057

Hoare

Characteristics of L-alanine:4 ...

Candida albicans, Candida albicans 3100, Saccharomyces cerevisiae, Saccharomyces cerevisiae 3059 S288C

Arch. Biochem. Biophys.

277

122-129

1990

-

-

-

-

-

1

3

2

2

-

4

4

-

8

-

-

2

-

-

-

1

1

16

2

2

-

-

-

1

-

-

2

-

1

-

-

-

-

2

-

-

1

-

3

-

2

2

-

4

4

-

-

-

2

-

-

1

1

16

2

2

-

-

-

1

-

-

1

-

-

-

-

-

-

640058

McKinney

Production of delta-aminolevul ...

Mus musculus, Mus musculus C57/BL6J

Int. J. Biochem.

22

347-357

1990

-

-

-

-

-

-

-

-

2

-

1

2

-

63

-

-

1

-

-

5

1

-

2

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

2

-

1

2

-

-

-

1

-

5

1

-

2

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

640055

Ades

Synthetic substrates for throm ...

Gallus gallus

Int. J. Biochem.

21

579-587

1989

-

-

-

-

-

-

-

2

2

-

1

1

-

1

-

-

1

-

-

2

-

-

1

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

2

2

-

1

1

-

-

-

1

-

2

-

-

1

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

640056

Prasad

-

Characterization of L-alanine: ...

Cenchrus americanus

Biochem. Int.

18

149-161

1989

-

-

-

-

-

-

3

2

-

-

2

-

-

1

-

-

-

-

-

1

-

-

1

1

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

3

-

2

-

-

2

-

-

-

-

-

-

1

-

-

1

1

-

-

-

-

-

-

-

-

-

-

-

-

-

-

640054

Rhee

L-alanine: 4,5-dioxovalerate a ...

Devosia riboflavina

J. Biochem.

103

1045-1049

1988

-

-

-

1

-

-

3

2

-

-

2

1

-

2

-

-

1

-

-

-

1

1

7

1

-

-

-

-

-

-

-

1

-

-

-

-

-

-

1

1

-

-

-

3

-

2

-

-

2

1

-

-

-

1

-

-

1

1

7

1

-

-

-

-

-

-

-

-

-

-

-

-

-

-

640053

Shanker

Affinity purification and prop ...

Rattus norvegicus, Rattus norvegicus Wistar

Arch. Biochem. Biophys.

248

652-657

1986

-

-

-

-

-

1

7

2

1

-

2

2

-

166

-

-

1

-

-

1

1

3

4

1

-

-

-

-

-

-

-

1

-

-

-

-

-

-

1

-

-

1

-

7

-

2

1

-

2

2

-

-

-

1

-

1

1

3

4

1

-

-

-

-

-

-

-

-

-

-

-

-

-

-

640051

Shanker

Evidence of hemin as an end pr ...

Rattus norvegicus, Rattus norvegicus Wistar

FEBS Lett.

189

129-132

1985

-

-

-

-

-

-

1

-

1

-

-

2

-

166

-

-

1

-

-

1

-

-

4

-

-

-

-

-

-

-

-

-

2

-

-

-

-

-

-

-

-

-

-

1

2

-

1

-

-

2

-

-

-

1

-

1

-

-

4

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

640052

Singh

Purification and characterizat ...

Rattus norvegicus

Biochim. Biophys. Acta

827

305-309

1985

-

-

-

-

-

-

2

2

-

-

2

1

-

2

-

-

1

-

-

2

1

-

1

1

1

-

-

-

1

-

-

-

-

-

-

-

-

-

-

-

-

-

-

2

-

2

-

-

2

1

-

-

-

1

-

2

1

-

1

1

1

-

-

-

1

-

-

-

-

-

-

-

-

-

640049

Shioi

-

Purification and characterizat ...

Raphanus sativus

Plant Cell Physiol.

25

1487-1493

1984

-

-

-

-

-

-

1

2

-

-

1

-

-

1

-

-

-

-

-

-

-

-

1

1

-

-

-

-

1

-

-

-

-

-

-

-

-

-

-

-

-

-

-

1

-

2

-

-

1

-

-

-

-

-

-

-

-

-

1

1

-

-

-

-

1

-

-

-

-

-

-

-

-

-

640050

Shioi

Purification and properties of ...

Chlorella regularis, Chlorella regularis S-50

Arch. Biochem. Biophys.

234

117-124

1984

-

-

-

-

-

1

6

4

-

-

2

2

-

7

-

-

1

-

-

-

1

2

12

1

-

-

1

-

1

-

-

-

1

1

-

-

-

-

-

-

-

1

-

6

1

4

-

-

2

2

-

-

-

1

-

-

1

2

12

1

-

-

1

-

1

-

-

1

-

-

-

-

-

-

640048

Bajkowski

delta-Aminolevulinic acid form ...

Clostridium tetanomorphum

J. Biol. Chem.

257

2207-2211

1982

-

-

-

-

-

-

9

2

-

-

5

1

-

3

-

-

1

-

-

-

1

-

5

1

-

-

-

-

-

-

-

1

-

-

-

-

-

-

1

-

-

-

-

9

-

2

-

-

5

1

-

-

-

1

-

-

1

-

5

1

-

-

-

-

-

-

-

-

-

-

-

-

-

-

640047

Noguchi

Biosynthesis of porphyrin prec ...

Bos taurus

J. Biol. Chem.

256

10335-10339

1981

-

-

-

-

-

-

5

4

1

-

4

1

-

1

-

-

1

-

-

1

1

2

3

1

-

-

1

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

5

-

4

1

-

4

1

-

-

-

1

-

1

1

2

3

1

-

-

1

-

-

-

-

-

-

-

-

-

-

-

640046

Varticovski

Biosynthesis of porphyrin prec ...

Bos taurus

J. Biol. Chem.

255

3742-3747

1980

-

-

-

1

-

1

6

2

2

-

1

1

-

1

-

-

1

-

-

1

1

-

11

-

-

-

-

-

1

-

-

1

-

-

-

-

-

-

1

1

-

1

-

6

-

2

2

-

1

1

-

-

-

1

-

1

1

-

11

-

-

-

-

-

1

-

-

-

-

-

-

-

-

-

640045

Neuberger

gamma, delta-Dioxovalerate ami ...

Rhodobacter sphaeroides

Biochim. Biophys. Acta

67

342-345

1963

-

-

-

-

-

1

25

2

-

-

-

1

-

2

-

-

1

-

-

-

-

1

7

-

-

-

-

-

1

-

-

-

-

-

-

-

-

-

-

-

-

1

-

25

-

2

-

-

-

1

-

-

-

1

-

-

-

1

7

-

-

-

-

-

1

-

-

-

-

-

-

-

-

-