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Literature summary for 2.6.1.42 extracted from
- Branched-chain amino acids: enzyme and substrate regulation (2006), J. Nutr., 136, 207S-211S.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| gabapentin | inhibitor of the cytosolic enzyme | Homo sapiens |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Homo sapiens | 5829 | - |
| mitochondrion | - |
Homo sapiens | 5739 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| glial cell | cytosolic enzyme form | Homo sapiens | - |
| neuron | mitochondrial enzyme form | Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-leucine + 2-oxoglutarate | - |
Homo sapiens | 4-methyl-2-oxopentanoate + L-glutamate | - |
? | |
| L-valine + 2-oxoglutarate | - |
Homo sapiens | 3-methyl-2-oxobutanoate + L-glutamate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| BCAA aminotransferase | - |
Homo sapiens |
| BcaT | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Homo sapiens | |
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Release 2023.1 (January 2023)
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