Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.6.1.42 extracted from

  • Xing, R.; Whitman, W.B.
    Characterization of enzymes of the branched-chain amino acid biosynthetic pathway in Methanococcus spp (1991), J. Bacteriol., 173, 2086-2092.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.6.1.42

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
150000
-
 gel filtration Methanococcus aeolicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-isoleucine + 2-oxoglutarate Methanococcus aeolicus
-
 3-methyl-2-oxopentanoate + L-glutamate
-
 r
L-isoleucine + 2-oxoglutarate Methanococcus maripaludis
-
 3-methyl-2-oxopentanoate + L-glutamate
-
 r
L-isoleucine + 2-oxoglutarate Methanococcus voltae
-
 3-methyl-2-oxopentanoate + L-glutamate
-
 r
L-leucine + 2-oxoglutarate Methanococcus aeolicus biosynthesis of the branched-chain amino acids L-valine, L-isoleucine and L-leucine 4-methyl-2-oxopentanoate + L-glutamate
-
 r
L-leucine + 2-oxoglutarate Methanococcus maripaludis biosynthesis of the branched-chain amino acids L-valine, L-isoleucine and L-leucine 4-methyl-2-oxopentanoate + L-glutamate
-
 r
L-leucine + 2-oxoglutarate Methanococcus voltae biosynthesis of the branched-chain amino acids L-valine, L-isoleucine and L-leucine 4-methyl-2-oxopentanoate + L-glutamate
-
 r
L-leucine + 2-oxoglutarate Methanococcus aeolicus last step in the biosynthesis of the branched-chain amino acids L-isoleucine, L-valine and L-leucine 4-methyl-2-oxopentanoate + L-glutamate
-
 r
L-valine + 2-oxoglutarate Methanococcus aeolicus
-
 3-methyl-2-oxobutanoate + L-glutamate
-
 r
L-valine + 2-oxoglutarate Methanococcus maripaludis
-
 3-methyl-2-oxobutanoate + L-glutamate
-
 r
L-valine + 2-oxoglutarate Methanococcus voltae
-
 3-methyl-2-oxobutanoate + L-glutamate
-
 r

Organism

Organism UniProt Comment Textmining
Methanococcus aeolicus
-
-
-
Methanococcus maripaludis
-
 JJ, DSM 2067
-
Methanococcus voltae
-
 PS, DSM 1537
-

Purification (Commentary)

Purification (Comment) Organism
partial Methanococcus aeolicus
partial Methanococcus maripaludis
partial Methanococcus voltae

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.006
-
-
 Methanococcus aeolicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-isoleucine + 2-oxo-3-methylpentanoate
-
 Methanococcus aeolicus 2-oxoisohexanoate + L-isoleucine
-
 r
L-isoleucine + 2-oxo-isopentanoate
-
 Methanococcus aeolicus 2-oxoisohexanoate + L-valine
-
 r
L-isoleucine + 2-oxoglutarate
-
 Methanococcus aeolicus 3-methyl-2-oxopentanoate + L-glutamate
-
 r
L-isoleucine + 2-oxoglutarate
-
 Methanococcus maripaludis 3-methyl-2-oxopentanoate + L-glutamate
-
 r
L-isoleucine + 2-oxoglutarate
-
 Methanococcus voltae 3-methyl-2-oxopentanoate + L-glutamate
-
 r
L-isoleucine + 2-oxoisohexanoate
-
 Methanococcus aeolicus 3-methyl-2-oxopentanoate + L-leucine
-
 r
L-leucine + 2-oxoglutarate
-
 Methanococcus aeolicus 4-methyl-2-oxopentanoate + L-glutamate
-
 r
L-leucine + 2-oxoglutarate
-
 Methanococcus maripaludis 4-methyl-2-oxopentanoate + L-glutamate
-
 r
L-leucine + 2-oxoglutarate
-
 Methanococcus voltae 4-methyl-2-oxopentanoate + L-glutamate
-
 r
L-leucine + 2-oxoglutarate biosynthesis of the branched-chain amino acids L-valine, L-isoleucine and L-leucine Methanococcus aeolicus 4-methyl-2-oxopentanoate + L-glutamate
-
 r
L-leucine + 2-oxoglutarate biosynthesis of the branched-chain amino acids L-valine, L-isoleucine and L-leucine Methanococcus maripaludis 4-methyl-2-oxopentanoate + L-glutamate
-
 r
L-leucine + 2-oxoglutarate biosynthesis of the branched-chain amino acids L-valine, L-isoleucine and L-leucine Methanococcus voltae 4-methyl-2-oxopentanoate + L-glutamate
-
 r
L-leucine + 2-oxoglutarate last step in the biosynthesis of the branched-chain amino acids L-isoleucine, L-valine and L-leucine Methanococcus aeolicus 4-methyl-2-oxopentanoate + L-glutamate
-
 r
L-valine + 2-oxoglutarate
-
 Methanococcus aeolicus 3-methyl-2-oxobutanoate + L-glutamate
-
 r
L-valine + 2-oxoglutarate
-
 Methanococcus maripaludis 3-methyl-2-oxobutanoate + L-glutamate
-
 r
L-valine + 2-oxoglutarate
-
 Methanococcus voltae 3-methyl-2-oxobutanoate + L-glutamate
-
 r

Synonyms

Synonyms Comment Organism
BcaT
-
 Methanococcus aeolicus