Cloned (Comment) | Organism |
---|---|
expression of complete gene cluster TdiA-TdiE in Escherichia coli, in order to establish the biosynthetic pathway to terrequinone A | Aspergillus nidulans |
Protein Variants | Comment | Organism |
---|---|---|
additional information | expression of complete gene cluster TdiA-TdiE in Escherichia coli, in order to establish the biosynthetic pathway to terrequinone A | Aspergillus nidulans |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.198 | - |
L-tryptophan | pH 7.8 | Aspergillus nidulans |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aspergillus nidulans | A7XRY8 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-tryptophan + phenylpyruvate | pyruvate, 2-oxoglutarate, and 2-oxo-(4-methylthio)butyrateare no co-substrates | Aspergillus nidulans | 3-indole-2-oxopropanoate + L-phenylalanine | for biosynthesis of terrequinone A, 3-indole-2-oxopropanoate is used for an unusual nonoxidative coupling by the tridomain nonribosomal peptide synthetase TdiA | ? |
Synonyms | Comment | Organism |
---|---|---|
TdiD | - |
Aspergillus nidulans |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0032 | - |
L-tryptophan | pH 7.8 | Aspergillus nidulans |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Aspergillus nidulans |