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Literature summary for 2.6.1.19 extracted from
- Subcellular localization and expression of multiple tomato gamma-aminobutyrate transaminases that utilize both pyruvate and glyoxylate (2009), J. Exp. Bot., 60, 3255-3267.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| full-length GABA-T1 isoform fused to the green fluorescent protein is expressed in Nicotiana tabacum, and GABA-T1 isoform is co-expressed with the GroES/EL molecular chaperone complex in Escherichia coli BL-21(DE3) Rosetta (pLysS) cells | Solanum lycopersicum |
| full-length GABA-T2 isoform fused to the green fluorescent protein is expressed in Nicotiana tabacum, and GABA-T2 isoform is co-expressed with the GroES/EL molecular chaperone complex in Escherichia coli BL-21(DE3) Rosetta (pLysS) cells | Solanum lycopersicum |
| full-length GABA-T3 isoform fused to the green fluorescent protein is expressed in Nicotiana tabacum, and GABA-T3 isoform is co-expressed with the GroES/EL molecular chaperone complex in Escherichia coli BL-21(DE3) Rosetta (pLysS) cells | Solanum lycopersicum |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | isoform GABA-T1 | Solanum lycopersicum | 5739 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Solanum lycopersicum | Q84P52 | - |
- |
| Solanum lycopersicum | Q84P53 | - |
- |
| Solanum lycopersicum | Q84P54 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Solanum lycopersicum |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| carpel | - |
Solanum lycopersicum | - |
| fruit | - |
Solanum lycopersicum | - |
| fruit | highest expression in ripe fruit leaf at day 92 | Solanum lycopersicum | - |
| fruit | highest expression of in ripe fruit leaf at day 92 | Solanum lycopersicum | - |
| leaf | - |
Solanum lycopersicum | - |
| petal | - |
Solanum lycopersicum | - |
| root | - |
Solanum lycopersicum | - |
| stamen | - |
Solanum lycopersicum | - |
| stem | - |
Solanum lycopersicum | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.0183 | - |
isoform GABA-T2, using pyruvate as amino cceptor | Solanum lycopersicum |
| 0.0209 | - |
isoform GABA-T2, using glyoxylate as amino cceptor | Solanum lycopersicum |
| 0.1785 | - |
isoform GABA-T3, using glyoxylate as amino acceptor | Solanum lycopersicum |
| 0.2065 | - |
isoform GABA-T3, using pyruvate as amino acceptor | Solanum lycopersicum |
| 3.495 | - |
isoform GABA-T1, using glyoxylate as amino acceptor | Solanum lycopersicum |
| 5.79 | - |
isoform GABA-T1, using pyruvate as amino acceptor | Solanum lycopersicum |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-aminobutanoate + glyoxylate | - |
Solanum lycopersicum | 4-oxobutanoate + glycine | - |
? |  |
| 4-aminobutanoate + pyruvate | - |
Solanum lycopersicum | 4-oxobutanoate + L-alanine | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| GABA-T1 | isoform | Solanum lycopersicum |
| GABA-T2 | isoform | Solanum lycopersicum |
| GABA-T3 | isoform | Solanum lycopersicum |
| gamma-aminobutyrate transaminases | - |
Solanum lycopersicum |
| gamma-aminobutyric acid transaminase | - |
Solanum lycopersicum |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Solanum lycopersicum | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | isoform GABA-T1 plays the predominant role in GABA metabolism in vegetative tissue | Solanum lycopersicum |
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