Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2,4-diaminobutanoate | not | Ovis aries | |
2,4-diaminobutanoate | not | Schistocerca gregaria | |
gabaculine | - |
Ovis aries | |
gabaculine | - |
Schistocerca gregaria | |
additional information | - |
Ovis aries | |
additional information | no inhibition by 3-aminopropane-1-sulfonic acid, isoguvacine (i.e. 1,2,3,4-tetrahydro-1-methyl-3-pyridine carboxylic acid), baclofen (i.e. beta-(aminomethyl)-4-chlorobenzenepropanoic acid), bicuculline, picrotoxin, Schistocerca gregaria: antiserum against sheep enzyme | Schistocerca gregaria | |
Muscimol | i.e. 5-(aminomethyl)-3-isoxazolol | Ovis aries | |
Muscimol | i.e. 5-(aminomethyl)-3-isoxazolol | Schistocerca gregaria |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.22 | - |
2-oxoglutarate | pH 8.5 | Ovis aries | |
0.27 | - |
2-oxoglutarate | pH 8.5 | Schistocerca gregaria | |
0.79 | - |
4-aminobutanoate | pH 8.5 | Schistocerca gregaria | |
2.2 | 2.3 | 4-aminobutanoate | - |
Ovis aries | |
2.2 | 2.3 | 4-aminobutanoate | pH 8.5 | Schistocerca gregaria |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Schistocerca gregaria | 5739 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
50000 | - |
2 * 50000, SDS-PAGE | Ovis aries |
97000 | - |
gel filtration | Ovis aries |
97000 | - |
gel filtration | Schistocerca gregaria |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Ovis aries | - |
- |
- |
Schistocerca gregaria | - |
locust | - |
Purification (Comment) | Organism |
---|---|
- |
Ovis aries |
- |
Schistocerca gregaria |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Ovis aries | - |
ganglion | supraoesophageal | Schistocerca gregaria | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
4.1 | - |
- |
Ovis aries |
4.36 | - |
- |
Schistocerca gregaria |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-aminobutanoate + 2-oxoglutarate | - |
Ovis aries | 4-oxobutanoate + L-glutamate | - |
r | |
4-aminobutanoate + 2-oxoglutarate | - |
Schistocerca gregaria | 4-oxobutanoate + L-glutamate | - |
r |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 50000, SDS-PAGE | Ovis aries |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
13.2 | - |
4-aminobutanoate | - |
Ovis aries |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
additional information | - |
pI: 5.5 | Ovis aries |
additional information | - |
pI: 6.7 | Schistocerca gregaria |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Ovis aries | |
pyridoxal 5'-phosphate | - |
Schistocerca gregaria |