Literature summary for 2.6.1.13 extracted from

da Silva, R.; Levillain, O.; Brosnan, J.T.; Araneda, S.; Brosnan, M.E.
The effect of portacaval anastomosis on the expression of glutamine synthetase and ornithine aminotransferase in perivenous hepatocytes (2013), Can. J. Physiol. Pharmacol., 91, 362-368.

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Application

Application	Comment	Organism
medicine	in rats, a liver portacaval shunt causes a marked decrease in glutamine synthetase activity and an increase in ornithine aminotransferase activity. The glutamine synthetase and ornithine aminotransferase proteins maintain their location in the perivenous cells, indicating that there is no generalized loss of perivenous hepatocytes, but rather, there is a significant alteration in the expression of these proteins and hence metabolism in this cell population	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	P04182	-	-

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Release 2023.1 (January 2023)