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Literature summary for 2.6.1.13 extracted from
- Adaptative response of nitrogen metabolism in early endotoxemia: role of ornithine aminotransferase (2010), Amino Acids, 39, 1417-1426.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| OAT | - |
Homo sapiens |
| ornithine aminotransferase | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | the influence of OAT activity in a model of septic shock induced by intraperitoneal injection of lipopolysaccharide in wild-type and transgenic mice overexpressing OAT in the liver, kidney and intestine is analysed. OAT overexpression has only limited metabolic consequences, most probably because of compensatory mechanisms ensuring amino acid homeostasis. OAT overexpression brings a metabolic advantage in the response to stress. Results show an inhibition of OAT activity and expression in the liver following LPS treatment | Homo sapiens |
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Release 2023.1 (January 2023)
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