Literature summary for 2.6.1.114 extracted from

Schwarz, J.; Konjik, V.; Jankowitsch, F.; Sandhoff, R.; Mack, M.
Identification of the key enzyme of roseoflavin biosynthesis (2016), Angew. Chem. Int. Ed. Engl., 55, 6103-6106 .

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
8-demethyl-8-formylriboflavin 5'-phosphate + H2O + acceptor	Streptomyces davaonensis	-	8-carboxy-8-demethylriboflavin 5'-phosphate + reduced acceptor	-	?
FMN + O2	Streptomyces davaonensis	-	8-demethyl-8-formylriboflavin 5'-phosphate + H2O	-	?
L-glutamate + 8-carboxy-8-demethylriboflavin 5'-phosphate + H2O + acceptor	Streptomyces davaonensis	-	2-oxoglutarate + 8-amino-8-demethylriboflavin 5'-phosphate + CO2 + reduced acceptor	-	?
L-glutamate + FMN + O2 + H2O + acceptor	Streptomyces davaonensis	-	2-oxoglutarate + 8-amino-8-demethylriboflavin 5'-phosphate + CO2 + reduced acceptor	-	?

Organism

Organism	UniProt	Comment	Textmining
Streptomyces davaonensis	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
8-demethyl-8-formylriboflavin 5'-phosphate + H2O + acceptor	-	Streptomyces davaonensis	8-carboxy-8-demethylriboflavin 5'-phosphate + reduced acceptor	-	?
FMN + O2	-	Streptomyces davaonensis	8-demethyl-8-formylriboflavin 5'-phosphate + H2O	-	?
L-glutamate + 8-carboxy-8-demethylriboflavin 5'-phosphate + H2O + acceptor	-	Streptomyces davaonensis	2-oxoglutarate + 8-amino-8-demethylriboflavin 5'-phosphate + CO2 + reduced acceptor	-	?
L-glutamate + FMN + O2 + H2O + acceptor	-	Streptomyces davaonensis	2-oxoglutarate + 8-amino-8-demethylriboflavin 5'-phosphate + CO2 + reduced acceptor	-	?

Synonyms

Synonyms	Comment	Organism
BN159_7989	-	Streptomyces davaonensis
rosB	-	Streptomyces davaonensis

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Release 2023.1 (January 2023)