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Literature summary for 2.6.1.11 extracted from

  • Voellmy, R.; Leisinger, T.
    Dual role for N-2-acetylornithine 5-aminotransferase from Pseudomonas aeruginosa in arginine biosynthesis and arginine catabolism (1975), J. Bacteriol., 122, 799-809.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.6.1.11

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information
-
 Pseudomonas aeruginosa

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
55000
-
 2 * 55000, SDS-PAGE Pseudomonas aeruginosa
105000
-
 thin-layer gel filtration, sucrose density gradient centrifugation Pseudomonas aeruginosa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
N-acetyl-L-glutamic gamma-semialdehyde + L-glutamate Pseudomonas aeruginosa fourth step in biosynthesis of arginine, arginine-repressible biosynthetic enzyme N2-acetyl-L-ornithine + 2-oxoglutarate
-
 ?
N2-acetyl-L-ornithine + 2-oxoglutarate Pseudomonas aeruginosa arginine degradation, arginine-inducible catabolic enzyme N-acetyl-L-glutamate-gamma-semialdehyde + L-glutamate
-
 ?

Organism

Organism UniProt Comment Textmining
Pseudomonas aeruginosa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
copurification of EC 2.6.1.11 and 2.6.1.13 Pseudomonas aeruginosa

Storage Stability

Storage Stability Organism
-20°C, partially purified enzyme is stable for at least 3 months Pseudomonas aeruginosa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information purified enzyme also has activity of EC 2.6.1.13 Pseudomonas aeruginosa ?
-
 ?
N-acetyl-L-glutamic gamma-semialdehyde + L-glutamate fourth step in biosynthesis of arginine, arginine-repressible biosynthetic enzyme Pseudomonas aeruginosa N2-acetyl-L-ornithine + 2-oxoglutarate
-
 ?
N2-acetyl-L-ornithine + 2-oxoglutarate arginine degradation, arginine-inducible catabolic enzyme Pseudomonas aeruginosa N-acetyl-L-glutamate-gamma-semialdehyde + L-glutamate
-
 ?
Nalpha-acetyl-L-ornithine + 2-oxoglutarate
-
 Pseudomonas aeruginosa N-acetyl-L-glutamate 5-semialdehyde + L-glutamate
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 55000, SDS-PAGE Pseudomonas aeruginosa

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.5
-
 N2-acetyl-L-ornithine Pseudomonas aeruginosa

pH Range

pH Minimum pH Maximum Comment Organism
6.5 10 pH 6.5: about 30% of activity maximum, pH 10.0: about 45% of activity maximum Pseudomonas aeruginosa