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Literature summary for 2.6.1.1 extracted from

  • Reidman, S.; Cohen, A.; Kupiec, M.; Weisman, R.
    The cytosolic form of aspartate aminotransferase is required for full activation of TOR complex 1 in fission yeast (2019), J. Biol. Chem., 294, 18244-18255 .
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Schizosaccharomyces pombe 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-aspartate + 2-oxoglutarate Schizosaccharomyces pombe
-
oxaloacetate + L-glutamate
-
?

Organism

Organism UniProt Comment Textmining
Schizosaccharomyces pombe
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-aspartate + 2-oxoglutarate
-
Schizosaccharomyces pombe oxaloacetate + L-glutamate
-
?

Synonyms

Synonyms Comment Organism
aspartate aminotransferase
-
Schizosaccharomyces pombe
CAA1
-
Schizosaccharomyces pombe

General Information

General Information Comment Organism
malfunction enzyme deficient fission yeast cells display auxotrophy to aspartate Schizosaccharomyces pombe
metabolism the catalytic activity of the enzyme is required for TOR complex 1 activation. The catalytic site of the enzyme is required for rapamycin resistance Schizosaccharomyces pombe