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Literature summary for 2.5.1.9 extracted from

  • Mitsuda, H.; Nakajima, K.; Nadamoto, T.; Yamada, Y.
    Riboflavin synthetase from Eremothecium ashbyii and a salvage pathway of the by-product in the enzyme reaction (1980), Methods Enzymol., 66, 307-323.
    View publication on PubMed
Search for more literature for 2.5.1.9

Activating Compound

Activating Compound Comment Organism Structure
diacetyl activates Eremothecium ashbyi

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6,7-dimethyl-8-ribityllumazine + 6,7-dimethyl-8-ribityllumazine Eremothecium ashbyi biosynthetic pathway riboflavin + 4-(1'-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine
-
 ?
additional information Eremothecium ashbyi salvage cycle for the by-product of the reaction is involved in the de novo synthesis of riboflavin ?
-
 ?

Organism

Organism UniProt Comment Textmining
Eremothecium ashbyi
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Eremothecium ashbyi

Reaction

Reaction Comment Organism Reaction ID
2 6,7-dimethyl-8-(1-D-ribityl)lumazine = riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine reaction mechanism Eremothecium ashbyi
a

Source Tissue

Source Tissue Comment Organism Textmining
mycelium
-
 Eremothecium ashbyi
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 various estimation methods Eremothecium ashbyi
0.16
-
 purified enzyme Eremothecium ashbyi

Storage Stability

Storage Stability Organism
frozen, mycelium, several months without loss of activity Eremothecium ashbyi

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6,7-dimethyl-8-ribityllumazine + 6,7-dimethyl-8-ribityllumazine
-
 Eremothecium ashbyi riboflavin + 4-(1'-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine
-
 ?
6,7-dimethyl-8-ribityllumazine + 6,7-dimethyl-8-ribityllumazine biosynthetic pathway Eremothecium ashbyi riboflavin + 4-(1'-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine
-
 ?
additional information
-
 Eremothecium ashbyi ?
-
 ?
additional information salvage cycle for the by-product of the reaction is involved in the de novo synthesis of riboflavin Eremothecium ashbyi ?
-
 ?