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Literature summary for 2.5.1.86 extracted from
- Functional characterization of long-chain prenyl diphosphate synthases from tomato (2013), Biochem. J., 449, 729-740.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| gene SlDPS, recombinant expression in Escherichia coli | Solanum lycopersicum |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | virus-induced gene silencing. The gene SlSPS is not able to complement silencing of gene SlSPS, encoding a solanesyl diphosphate synthase, EC 2.5.1.85 | Solanum lycopersicum |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Solanum lycopersicum | the enzyme can utilize geranyl, farnesyl or geranylgeranyl diphosphates in the synthesis of C45 and C50 prenyl diphosphates | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Solanum lycopersicum | - |
gene SlDPS | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (2Z,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate | enzyme SlDPS extends the prenyl chain length of the endogenous ubiquinone to ten isoprene units | Solanum lycopersicum | 7 diphosphate + trans,octacis-decaprenyl diphosphate | - |
? | |
| additional information | the enzyme can utilize geranyl, farnesyl or geranylgeranyl diphosphates in the synthesis of C45 and C50 prenyl diphosphates | Solanum lycopersicum | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| decaprenyl diphosphate synthase | - |
Solanum lycopersicum |
| long-chain prenyl diphosphate synthase | - |
Solanum lycopersicum |
| SlDPS | - |
Solanum lycopersicum |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | plants silenced for SlSPS are not affected in leaf appearance, but impacted on primary metabolism | Solanum lycopersicum |
| metabolism | requirement for two long-chain prenyl diphosphate synthases in the tomato, i.e. SlSPS, a solanesyl diphosphate synthase, EC 2.5.1.85, and SlDPS, a decaprenyl diphosphate synthase | Solanum lycopersicum |
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Release 2023.1 (January 2023)
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