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Literature summary for 2.5.1.82 extracted from

  • Sun, H.Y.; Ko, T.P.; Kuo, C.J.; Guo, R.T.; Chou, C.C.; Liang, P.H.; Wang, A.H.
    Homodimeric hexaprenyl pyrophosphate synthase from the thermoacidophilic crenarchaeon Sulfolobus solfataricus displays asymmetric subunit structures (2005), J. Bacteriol., 187, 8137-8148.
    View publication on PubMedView publication on EuropePMC

Crystallization (Commentary)

Crystallization (Comment) Organism
D81C and W136E mutant crystals are grown at room temperature by the hanging drop vapor diffusion method from a reservoir solution containing 10% (w/v) polyethyleneglycol 8000, 2.4 M lithium chloride, and 100 mM Tris (pH 8.0). Crystal structure of the homodimeric C30-HexPPs resembles those of other trans-prenyltransferases, including farnesyl pyrophosphate synthase (FPPs) and octaprenyl pyrophosphate synthase Saccharolobus solfataricus

Protein Variants

Protein Variants Comment Organism
D81C crystal structure of mutant enzyme Saccharolobus solfataricus
W136E crystal structure of mutant enzyme Saccharolobus solfataricus

Organism

Organism UniProt Comment Textmining
Saccharolobus solfataricus Q97W92
-
-
Saccharolobus solfataricus P2 Q97W92
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Saccharolobus solfataricus

Subunits

Subunits Comment Organism
homodimer
-
Saccharolobus solfataricus

Synonyms

Synonyms Comment Organism
hexaprenyl pyrophosphate synthase
-
Saccharolobus solfataricus
HexPPs
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Saccharolobus solfataricus