Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
76000 | - |
gel filtration | Natronomonas pharaonis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
geranylgeranyl diphosphate + isopentenyl diphosphate | Natronomonas pharaonis | the enzyme may synthesize a precursor for the C25 moiety of C20,C25 diether lipids | (2E,6E,10E,14E)-geranylfarnesyl diphosphate + diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Natronomonas pharaonis | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Natronomonas pharaonis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(2E,6E)-farnesyl diphosphate + 2 isopentenyl diphosphate | farnesyl diphosphate shows 93% of the activity with geranylgeranyl diphosphate. Stereochemistry of farnesylgeranyl diphosphate synthesized by FGPP synthase is unclear, but may be an all-E isomer because the same isomer is produced when dimethylallyl diphosphate, geranyl diphosphate, and (all-E)-farnesyl diphosphate, as well as (all-E)-geranylgeranyl diphosphate, are used as substrates. The stereochemistry of the C25 moiety of C20,C25-diether lipids is identical with that of the C20 moiety | Natronomonas pharaonis | (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 2 diphosphate | - |
? | |
dimethylallyl diphosphate + 4 isopentenyl diphosphate | dimethylallyl diphosphate shows 51% of the activity with farnesyl diphosphate. Stereochemistry of farnesylgeranyl diphosphate synthesized by FGPP synthase is unclear, but may be an all-E isomer because the same isomer is produced when dimethylallyl diphosphate, geranyl diphosphate, and (all-E)-farnesyl diphosphate, as well as (all-E)-geranylgeranyl diphosphate, are used as substrates. The stereochemistry of the C25 moiety of C20,C25-diether lipids is identical with that of the C20 moiety | Natronomonas pharaonis | (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 4 diphosphate | large amounts of intermediates are formed: geranyl diphosphate, farnesyl diphosphate, geranylgeranyl diphosphate | ? | |
geranyl diphosphate + 3 isopentenyl diphosphate | geranyl diphosphate shows 81% of the activity with farnesyl diphosphate. Stereochemistry of farnesylgeranyl diphosphate synthesized by FGPP synthase is unclear, but may be an all-E isomer because the same isomer is produced when dimethylallyl diphosphate, geranyl diphosphate, and (all-E)-farnesyl diphosphate, as well as (all-E)-geranylgeranyl diphosphate, are used as substrates. The stereochemistry of the C25 moiety of C20,C25-diether lipids is identical with that of the C20 moiety | Natronomonas pharaonis | (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 3 diphosphate | - |
? | |
geranylgeranyl diphosphate + isopentenyl diphosphate | the enzyme may synthesize a precursor for the C25 moiety of C20,C25 diether lipids | Natronomonas pharaonis | (2E,6E,10E,14E)-geranylfarnesyl diphosphate + diphosphate | - |
? | |
geranylgeranyl diphosphate + isopentenyl diphosphate | geranylgeranyl diphosphate is the allylic substrate with the highest activity. Stereochemistry of farnesylgeranyl diphosphate synthesized by FGPP synthase is unclear, but may be an all-E isomer because the same isomer is produced when dimethylallyl diphosphate, geranyl diphosphate, and (all-E)-farnesyl diphosphate, as well as (all-E)-geranylgeranyl diphosphate, are used as substrates. The stereochemistry of the C25 moiety of C20,C25-diether lipids is identical with that of the C20 moiety | Natronomonas pharaonis | (2E,6E,10E,14E)-geranylfarnesyl diphosphate + diphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
farnesyl diphosphate synthase | - |
- |
FGPP synthase | - |
Natronomonas pharaonis |